SCHEMBL6905745

SCHEMBL6905745

Oc1ccc2c(c1O)Cc1ccc(O)c(O)c1C2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA6 P23280 2/20 0.36
EGFR P00533 2/20 0.36
PIM1 P11309 1/20 0.36
ADAMTS4 O75173 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
FYN P06241 1/20 0.36
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
MMP8 P22894 1/20 0.36
CDK2 P24941 1/20 0.36
MMP12 P39900 1/20 0.36
RECQL P46063 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ADAMTS5 Q9UNA0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6905783 0.89 RAC1 (0.41) CA1CA2CA6FYNCA4
SCHEMBL7271975 0.76 EGFR (0.42) EGFRALDH1A1HPGDALOX15TDP1
SCHEMBL21092188 0.72 DRD2 (0.33) CA1CA2CA6EGFRPIM1
SCHEMBL3797823 0.72 BCL2L1 (0.56) DRD2DRD1
SCHEMBL10534995 0.71
SCHEMBL1261848 0.71 PNMT (0.50) CA1CA2CA6ALDH1A1LMNA
SCHEMBL29927125 0.71 PNMT (0.50) CA1CA2CA6ALDH1A1LMNA
SCHEMBL9404792 0.70 DRD2 (0.33) CA1CA2CA6EGFRPIM1
SCHEMBL17629428 0.70 PNMT (0.41) CA1CA2CA6ALDH1A1HPGD
SCHEMBL8542055 0.67 FYN (0.50) CA1CA2FYNHSD17B10DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed