Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.47 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906238 | 1.00 | GRM2 (0.47) | GRM2GRM3KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6909803 | 0.92 | GRM2 (0.36) | GRM2GRM3KMT2AMEN1GRM6 | |
| SCHEMBL6909800 | 0.92 | GRM2 (0.36) | GRM2GRM3KMT2AMEN1GRM6 | |
| SCHEMBL6911744 | 0.91 | GRM2 (0.38) | GRM2GRM3GRM6GRM4L3MBTL1 | |
| SCHEMBL6901983 | 0.91 | GRM2 (0.40) | GRM2GRM3SMN1; SMN2GRM6GRM4 | |
| SCHEMBL6911749 | 0.91 | GRM2 (0.38) | GRM2GRM3GRM6GRM4L3MBTL1 | |
| SCHEMBL6901988 | 0.91 | GRM2 (0.40) | GRM2GRM3SMN1; SMN2GRM6GRM4 | |
| SCHEMBL6916637 | 0.90 | GRM2 (0.47) | GRM2GRM3KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6916632 | 0.90 | GRM2 (0.47) | GRM2GRM3KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6904292 | 0.90 | GRM2 (0.43) | GRM2GRM3KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |