Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 5/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 5/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6911749 | 1.00 | GRM2 (0.38) | GRM2GRM3GRM6GRM4NPC1 | |
| SCHEMBL6901983 | 0.93 | GRM2 (0.40) | GRM2GRM3GRM6GRM4RAB9A | |
| SCHEMBL6901988 | 0.93 | GRM2 (0.40) | GRM2GRM3GRM6GRM4RAB9A | |
| SCHEMBL6906235 | 0.91 | GRM2 (0.47) | GRM2GRM3GRM6GRM4NPC1 | |
| SCHEMBL6916632 | 0.91 | GRM2 (0.47) | GRM2GRM3GRM6GRM4NPC1 | |
| SCHEMBL6916637 | 0.91 | GRM2 (0.47) | GRM2GRM3GRM6GRM4NPC1 | |
| SCHEMBL6906238 | 0.91 | GRM2 (0.47) | GRM2GRM3GRM6GRM4NPC1 | |
| SCHEMBL6910269 | 0.91 | GRM2 (0.50) | GRM2GRM3GRM6GRM4NPC1 | |
| SCHEMBL6910265 | 0.91 | GRM2 (0.50) | GRM2GRM3GRM6GRM4NPC1 | |
| SCHEMBL6906145 | 0.90 | TAS1R3 (0.45) | GRM2GRM3GRM6GRM4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |