Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRN | P28799 | 2/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.32 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.32 |
| ▸ | RELA | Q04206 | 3/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6909803 | 1.00 | GRM2 (0.36) | GRM2GRM3TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6906235 | 0.92 | GRM2 (0.47) | GRM2GRM3TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL6906238 | 0.92 | GRM2 (0.47) | GRM2GRM3TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL6904297 | 0.92 | GRM2 (0.43) | GRM2GRM3TAS1R3TAS1R1HSD11B1 | |
| SCHEMBL6904292 | 0.92 | GRM2 (0.43) | GRM2GRM3TAS1R3TAS1R1HSD11B1 | |
| SCHEMBL6912130 | 0.90 | TAS1R3 (0.35) | GRM2GRM3TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6912129 | 0.90 | TAS1R3 (0.35) | GRM2GRM3TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6914733 | 0.89 | TAS1R3 (0.42) | GRM2GRM3TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6914736 | 0.89 | TAS1R3 (0.42) | GRM2GRM3TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6913681 | 0.88 | GRM2 (0.37) | GRM2GRM3TAS1R3TAS1R1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |