SCHEMBL6906251

SCHEMBL6906251

N#CSC(SC#N)Sc1nc2ccccc2s1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.54
ALDH1A1 P00352 6/20 0.54
ALOX15 P16050 4/20 0.54
HSD17B10 Q99714 4/20 0.54
FBP1 P09467 3/20 0.54
TDP1 Q9NUW8 2/20 0.54
ADRA2A P08913 1/20 0.54
ADORA3 P0DMS8 1/20 0.54
DRD2 P14416 1/20 0.54
ADRA2B P18089 1/20 0.54
ADRA2C P18825 1/20 0.54
DRD1 P21728 1/20 0.54
MC5R P33032 1/20 0.54
OPRM1 P35372 1/20 0.54
DRD3 P35462 1/20 0.54
OPRK1 P41145 1/20 0.54
CCR2 P41597 1/20 0.54
HTR6 P50406 1/20 0.54
SLC6A3 Q01959 1/20 0.54
PDK1 Q15118 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9067753 0.86 ALDH1A1 (0.53) HPGDALDH1A1ALOX15HSD17B10FBP1
SCHEMBL10358349 0.81 HPGD (0.58) HPGDALDH1A1ALOX15HSD17B10FBP1
SCHEMBL7910140 0.78 ALDH1A1 (0.63) HPGDALDH1A1ALOX15HSD17B10FBP1
SCHEMBL2634521 0.78 HPGD (0.54) HPGDALDH1A1ALOX15HSD17B10FBP1
SCHEMBL10358647 0.78 ALDH1A1 (0.54) HPGDALDH1A1ALOX15HSD17B10FBP1
Methane SCHEMBL28380474 0.77 ALDH1A1 (0.61) HPGDALDH1A1ALOX15HSD17B10FBP1
SCHEMBL8176143 0.76 HPGD (0.70) HPGDALDH1A1ALOX15HSD17B10FBP1
SCHEMBL15003935 0.75 ALDH1A1 (0.63) HPGDALDH1A1ALOX15HSD17B10FBP1
SCHEMBL10927242 0.75 ALDH1A1 (0.63) HPGDALDH1A1ALOX15HSD17B10FBP1
SCHEMBL10644534 0.75 ALDH1A1 (0.50) HPGDALDH1A1ALOX15HSD17B10FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240389587-A1 COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (INRAE) (FR) 2024-11-28 US disclosed
EP-4440313-A1 COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS Institut national de recherche pour l'agriculture, L'alimentation et l'environnement (INRAE) (FR) 2024-10-09 EP disclosed
CN-118714927-A Compositions and methods for controlling phytopathogenic infection 法国国家农业食品与环境研究院 2024-09-27 CN disclosed
WO-2023099609-A1 COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (INRAE) (FR) 2023-06-08 WO disclosed
EP-4186367-A1 COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS Institut national de recherche pour l'agriculture, l'alimentation et l'environnement (INRAE) (FR) 2023-05-31 EP disclosed
EP-3025583-B1 BAIT COMPOSITIONS AND METHODS FOR CONTROLLING A PEST BY PHYSICAL EFFECTS BioGenius GmbH (DE) 2017-09-27 EP disclosed
US-20160150775-A1 BAIT COMPOSITIONS AND METHODS FOR CONTROLLING A PEST BY PHYSICAL EFFECTS BioGenius GmbH (DE) 2016-06-02 US disclosed
EP-3025583-A1 BAIT COMPOSITIONS AND METHODS FOR CONTROLLING A PEST BY PHYSICAL EFFECTS BioGenius GmbH (DE) 2016-06-01 EP disclosed
EP-1416792-A1 WATER-IN-OIL POLYMER DISPERSION AS ADDITIVE IN COMPOSITIONS CONTAINING ACTIVE INGREDIENTS Goldschmidt AG (DE) 2004-05-12 EP disclosed
US-20030118614-A1 Water-in-oil polymer dispersion as additive in active ingredient-comprising compositions GOLDSCHMIDT AG (DE) 2003-06-26 US disclosed
WO-2003015512-A1 WATER-IN-OIL POLYMER DISPERSION AS ADDITIVE IN COMPOSITIONS CONTAINING ACTIVE INGREDIENTS GOLDSCHMIDT AG (DE) 2003-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240389587-A1 COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS XBP1, ERN1, ERN2 HPGD 2031/4885ALDH1A1 4442/4885ALOX15 1500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.