SCHEMBL7910140

SCHEMBL7910140

N#CSc1nc2ccccc2s1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.63
HPGD P15428 5/20 0.63
HSD17B10 Q99714 5/20 0.63
ALOX15 P16050 4/20 0.63
FBP1 P09467 3/20 0.63
ADRA2A P08913 1/20 0.63
ADORA3 P0DMS8 1/20 0.63
DRD2 P14416 1/20 0.63
ADRA2B P18089 1/20 0.63
ADRA2C P18825 1/20 0.63
DRD1 P21728 1/20 0.63
MC5R P33032 1/20 0.63
OPRM1 P35372 1/20 0.63
DRD3 P35462 1/20 0.63
OPRK1 P41145 1/20 0.63
CCR2 P41597 1/20 0.63
HTR6 P50406 1/20 0.63
SLC6A3 Q01959 1/20 0.63
PDK1 Q15118 1/20 0.63
TDP1 Q9NUW8 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL28380474 0.98 ALDH1A1 (0.61) ALDH1A1HPGDHSD17B10ALOX15FBP1
SCHEMBL8176143 0.82 HPGD (0.70) ALDH1A1HPGDHSD17B10ALOX15FBP1
SCHEMBL3096374 0.81 ALDH1A1 (0.63) ALDH1A1HPGDHSD17B10ALOX15FBP1
SCHEMBL2034336 0.79 ALDH1A1 (0.70) ALDH1A1HPGDHSD17B10ALOX15FBP1
SCHEMBL8887013 0.78 CYP1A2 (0.73) ALDH1A1HPGDHSD17B10ALOX15FBP1
SCHEMBL6906251 0.78 HPGD (0.54) ALDH1A1HPGDHSD17B10ALOX15FBP1
SCHEMBL54175 0.78 CYP1A2 (0.73) ALDH1A1HPGDHSD17B10ALOX15FBP1
SCHEMBL29352673 0.78 CYP1A2 (0.73) ALDH1A1HPGDHSD17B10ALOX15FBP1
Benzothiazyl Disulfide SCHEMBL11095350 0.78 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10ALOX15FBP1
Benzothiazyl Disulfide SCHEMBL23527 0.78 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10ALOX15FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204225-B1 FOR LUBRICATION OF METAL CUTTING AND FORMING TOOLS; TO PROVIDE COOLING FOR TOOLING, REMOVAL OF CUT CHIPS OR FRAGMENTS AWAY FROM TOOL/WORK PIECE INTERFACE, TO PROVIDE AN ACCEPTABLE POST-MACHINING FINISHED SURFACE MIDWEST BIOLOGICALS, INC. 2001-03-20 US claimed
US-5451398-A Ophthalmic and disinfecting compositions and methods for preserving and using same ALLERGAN, INC. (US) 1995-09-19 US claimed
CN-115052482-A Compositions having pesticidal utility and methods relating thereto 科迪华农业科技有限责任公司 2022-09-13 CN disclosed
CN-108699050-B Benzoxazole compound or salt thereof, agricultural and horticultural insecticide containing said compound, and method for using said insecticide 日本农药株式会社 2021-06-11 CN disclosed
CN-112236421-A Pyrazole derivative and pest control agent 组合化学工业株式会社 2021-01-15 CN disclosed
CN-107531622-B Anthranilate compound or salt thereof, agricultural and horticultural bactericide containing anthranilate compound, and method for using same 日本农药株式会社 2020-03-20 CN disclosed
CN-110612295-A Pyrazole-3-carboxylic acid amide derivative and pest control agent 组合化学工业株式会社 2019-12-24 CN disclosed
EP-3317257-B1 SUBSTITUTED IMIDAZOLIUM SULFURANES AND THEIR USE STUDIENGESELLSCHAFT KOHLE MBH (DE) 2019-05-15 EP disclosed
US-6204225-B1 FOR LUBRICATION OF METAL CUTTING AND FORMING TOOLS; TO PROVIDE COOLING FOR TOOLING, REMOVAL OF CUT CHIPS OR FRAGMENTS AWAY FROM TOOL/WORK PIECE INTERFACE, TO PROVIDE AN ACCEPTABLE POST-MACHINING FINISHED SURFACE MIDWEST BIOLOGICALS, INC. 2001-03-20 US disclosed
US-5451398-A Ophthalmic and disinfecting compositions and methods for preserving and using same ALLERGAN, INC. (US) 1995-09-19 US disclosed
EP-0433616-A2 Use of heterocyclic thiocyanates as microbicides and agents containing such microbicides Degussa Aktiengesellschaft (DE) 1991-06-26 EP disclosed
US-4028374-A Antibacterial thiocyanatobenzothiazoles MORTON-NORWICH PRODUCTS, INC. (US) 1977-06-07 US disclosed
US-4028374-A Antibacterial thiocyanatobenzothiazoles MORTON-NORWICH PRODUCTS, INC. (US) 1977-06-07 US disclosed
US-4028374-A Antibacterial thiocyanatobenzothiazoles MORTON-NORWICH PRODUCTS, INC. (US) 1977-06-07 US disclosed