Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | PKLR | P30613 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516332 | 0.86 | HSD17B10 (0.53) | MAPTGAAPKLRPOLBHSP90AA1 | |
| SCHEMBL9713722 | 0.82 | BACE1 (0.56) | MAPTGAAPOLBMEN1MAOA | |
| SCHEMBL29429256 | 0.82 | BACE1 (0.56) | MAPTGAAPOLBMEN1MAOA | |
| SCHEMBL1070330 | 0.82 | BACE1 (0.56) | MAPTGAAPOLBMEN1MAOA | |
| SCHEMBL29706496 | 0.75 | ALDH1A1 (0.63) | MAPTPOLBBCL2MCL1MEN1 | |
| SCHEMBL30501700 | 0.75 | ALDH1A1 (0.63) | MAPTPOLBBCL2MCL1MEN1 | |
| SCHEMBL14760441 | 0.74 | ESR1 (0.53) | MAPTGAAPOLBMAOAALDH1A1 | |
| SCHEMBL8516709 | 0.74 | ALDH1A1 (0.63) | MAPTGAAPKLRALDH1A1HPGD | |
| SCHEMBL1346857 | 0.73 | HTR6 (0.58) | MAPTGAAPKLRPOLBMEN1 | |
| SCHEMBL30110766 | 0.73 | SERPINE1 (0.64) | MAPTGAAPKLRPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785235-B1 | Compatibilized blends of polyetherimides and liquid crystalline polyesters | GEN ELECTRIC (US) | 2004-03-31 | — | — | EP | disclosed |
| US-6570038-B1 | Phase transfer agent; reacting phosgene with sceondary amine | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2003-05-27 | — | — | US | disclosed |
| EP-0784051-B1 | Aqueous hexasubstituted guanidinium chlorides and methods for their preparation and use | GEN ELECTRIC (US) | 2002-08-07 | — | — | EP | disclosed |
| US-6235934-B1 | MIXTURE WITH IMIDE AND SOLVENT | GENERAL ELECTRIC COMPANY | 2001-05-22 | — | — | US | disclosed |
| US-5872294-A | Aqueous hexasubstituted guanidinium chlorides and methods for their preparation and use | GENERAL ELECTRIC COMPANY (US) | 1999-02-16 | — | — | US | disclosed |
| EP-0785235-A2 | Compatibilized blends of polyetherimides and liquid crystalline polyesters | GENERAL ELECTRIC COMPANY (US) | 1997-07-23 | — | — | EP | disclosed |
| EP-0784051-A1 | Aqueous hexasubstituted guanidinium chlorides and methods for their preparation and use | GENERAL ELECTRIC COMPANY (US) | 1997-07-16 | — | — | EP | disclosed |
| US-5633319-A | NON-DELAMINATING; LOW VISCOSITY, HIGH WORKABILITY | GENERAL ELECTRIC COMPANY (US) | 1997-05-27 | — | — | US | disclosed |
| US-5132423-A | Nucleophilic substitution reaction of alkali hydroxy- or mercaptoaromatic compound and heterocyclic substituted imide | GENERAL ELECTRIC COMPANY (US) | 1992-07-21 | — | — | US | disclosed |
| US-5116975-A | Bis(guanidinium)alkane salts as phase transfer catalysts | GENERAL ELECTRIC COMPANY (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0254994-B1 | POLYETHERIMIDE BISHALOFORMATE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5081298-A | Bis(pentaalkylguanidinium) alkane salts as phase transfer catalysts | GENERAL ELECTRIC COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| US-4757150-A | Polyetherimide bisphenol compositions | GENERAL ELECTRIC COMPANY (US) | 1988-07-12 | — | — | US | disclosed |
| EP-0254994-A1 | Polyetherimide bishaloformate compositions | GENERAL ELECTRIC COMPANY (US) | 1988-02-03 | — | — | EP | disclosed |