SCHEMBL6906352

SCHEMBL6906352

O=C1c2ccccc2C(Cc2ccccc2)c2ccccc21

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 1/20 0.47
EDNRA P25101 1/20 0.47
EP300 Q09472 1/20 0.44
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CDC25B P30305 1/20 0.42
HTR2A P28223 1/20 0.42
PTPN1 P18031 1/20 0.42
CYP1A2 P05177 1/20 0.41
MAPK1 P28482 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
PARK7 Q99497 1/20 0.41
MAOB P27338 1/20 0.40
KDM4E B2RXH2 1/20 0.40
NSD2 O96028 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3918548 0.87 HTR2A (0.54) EP300MEN1KMT2AHTR2ACA1
SCHEMBL17022656 0.81 HTR2A (0.56) HTR2ACA1CA2KDM4EMAPT
SCHEMBL18994257 0.80 CYP1A2 (0.48) EP300MEN1KMT2ACYP1A2MAOB
Alcohol SCHEMBL16265494 0.78 HTR2A (0.45) HTR2AMAPT
SCHEMBL9055148 0.77 MAPT (0.52) EP300MEN1KMT2ACYP1A2MAPK1
SCHEMBL24270335 0.75 MAOB (0.47) EDNRBEDNRAMEN1KMT2AMAPK1
SCHEMBL6903762 0.75 CDC25B (0.46) EDNRBEDNRAMEN1KMT2ACDC25B
SCHEMBL17500281 0.74 RXRA (0.49) HTR2AALDH1A1MAPTCES2
SCHEMBL31653961 0.74 EP300 (0.44) EP300MEN1KMT2AMAPK1POLB
SCHEMBL8111113 0.72 CYP19A1 (0.47) HTR2ACYP1A2CA1CA2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60084384-A None JP disclosed
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed
JP-S6084384-A METHOD FOR STABILIZING ORGANIC COMPOUND MITSUI PETROCHEM IND LTD 1985-05-13 JP disclosed