Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335854 | 0.86 | LMNA (0.42) | LMNAMMEHRH1TRPA1 | |
| SCHEMBL336626 | 0.84 | CYP2D6 (0.40) | RIPK1LMNACYP3A4CYP2C19CYP1A2 | |
| SCHEMBL6682969 | 0.73 | KIF11 (0.42) | RIPK1LMNACYP3A4CYP2C19CYP2D6 | |
| SCHEMBL28500896 | 0.67 | LMNA (0.43) | LMNAMMETRPA1 | |
| SCHEMBL29002686 | 0.67 | TAAR1 (0.54) | LMNAMMEHRH1SLC6A3SLC6A4 | |
| SCHEMBL27416933 | 0.67 | LMNA (0.43) | LMNAMMETRPA1 | |
| SCHEMBL1176305 | 0.67 | LMNA (0.43) | RIPK1LMNACYP3A4CYP2C19CYP1A2 | |
| SCHEMBL27802789 | 0.66 | CYP2C19 (0.43) | LMNACYP3A4CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL27823460 | 0.66 | KIF11 (0.38) | RIPK1CYP3A4CYP2C19TSHRCYP2D6 | |
| SCHEMBL335892 | 0.66 | TAAR1 (0.41) | RIPK1LMNACYP2D6HRH1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1141049-B1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION | BASELL POLYOLEFINE GMBH (DE) | 2004-06-09 | — | — | EP | disclosed |
| EP-1141049-A1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION | Basell Technology Company B.V. (NL) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035974-A1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2000-06-22 | — | — | WO | disclosed |