Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 9/20 | 0.65 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ESRRB | O95718 | 1/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900534 | 0.88 | SLC18A3 (0.50) | ESR2SLC18A3CYP3A4CYP2C9ESR1 | |
| SCHEMBL5284 | 0.88 | SLC18A3 (0.50) | ESR2SLC18A3CYP3A4CYP2C9ESR1 | |
| SCHEMBL1128088 | 0.88 | SLC18A3 (0.50) | ESR2SLC18A3CYP3A4CYP2C9ESR1 | |
| Hydrochloric Acid SCHEMBL20543303 | 0.85 | SLC18A3 (0.48) | ESR2SLC18A3CYP3A4CYP2C9ESR1 | |
| Cyanide SCHEMBL27748394 | 0.81 | SLC18A3 (0.46) | ESR2SLC18A3CYP3A4CYP2C9ESR1 | |
| SCHEMBL605342 | 0.79 | ESR2 (1.00) | ESR2CYP3A4CYP2C9ESR1 | |
| SCHEMBL7923165 | 0.79 | KDM1A (0.50) | ESR2SLC18A3CYP3A4CYP2C9ESR1 | |
| SCHEMBL1624197 | 0.79 | SLC18A3 (0.44) | ESR2SLC18A3CYP3A4ESR1MEN1 | |
| SCHEMBL1624198 | 0.79 | SLC18A3 (0.44) | ESR2SLC18A3CYP3A4ESR1MEN1 | |
| SCHEMBL178486 | 0.79 | ESR2 (1.00) | ESR2CYP3A4CYP2C9ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107573249-B | A kind of preparation method of trans- 4- alkoxy cyclohexylamine | 上海馨远医药科技有限公司 | 2018-12-25 | — | — | CN | claimed |
| WO-2023088406-A1 | FUSED IMIDE DERIVATIVE | 正大天晴药业集团股份有限公司 | 2023-05-25 | — | — | WO | disclosed |
| CN-109796409-A | A kind of method of tetrahydrobiopterin synthesis indazole compound | 广州暨南生物医药研究开发基地有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-107573249-B | A kind of preparation method of trans- 4- alkoxy cyclohexylamine | 上海馨远医药科技有限公司 | 2018-12-25 | — | — | CN | disclosed |
| CN-109054427-A | A kind of dyestuff, ink and electric moistening display part | 深圳市国华光电科技有限公司 | 2018-12-21 | — | — | CN | disclosed |
| US-20180119279-A1 | PROCESS FOR PRODUCING FLEXIBLE ORGANIC-INORGANIC LAMINATES | BASF COATINGS GMBH (DE) | 2018-05-03 | — | — | US | disclosed |
| US-20180119279-A1 | PROCESS FOR PRODUCING FLEXIBLE ORGANIC-INORGANIC LAMINATES | BASF COATINGS GMBH (DE) | 2018-05-03 | — | — | US | disclosed |
| CN-107573249-A | A kind of preparation method of trans 4 alkoxy cyclohexylamine | 上海馨远医药科技有限公司 | 2018-01-12 | — | — | CN | disclosed |
| CN-104710420-B | Azabicyclic formula compound or its salt, containing its medicine, compositions and application | 大鹏药品工业株式会社 | 2016-07-27 | — | — | CN | disclosed |
| CN-102471335-B | Azanebicyclic compound or salt thereof | TAIHO PHARMACEUTICAL CO.,LTD. (JP) | 2015-09-30 | — | — | CN | disclosed |
| CN-104710420-A | Azabicyclo compound and salt thereof, medication and composition containing same, and application thereof | TAIHO PHARMACEUTICAL CO LTD | 2015-06-17 | — | — | CN | disclosed |
| EP-0939070-B1 | Process for the preparation of six-ring carbocyclic compounds | BAYER MATERIALSCIENCE AG (DE) | 2004-06-23 | — | — | EP | disclosed |
| US-6255530-B1 | RING HYDROGENATING AN AROMATIC COMPOUND IN AN IMMISCIBLE PHASE IN WHICH HYDROGEN IS DISPERSED IN A REACTION SYSTEM COMPRISING A FIRST AND SECOND PHASE THAT FORMS TWO LIQUIDS;METAL COLLOID CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-03 | — | — | US | disclosed |
| US-4275184-A | HYDROSILATION OF POLYDIMETHYL SILOXANE | RHONE-POULENC INDUSTRIES (FR) | 1981-06-23 | — | — | US | disclosed |
| US-4263436-A | Polyethylene silicon compounds | RHONE-POULENC INDUSTRIES (FR) | 1981-04-21 | — | — | US | disclosed |
| US-4213914-A | ADDITION-CONDENSATION COPOLYMERS | RHONE-POULENC INDUSTRIES (FR) | 1980-07-22 | — | — | US | disclosed |
| US-4208342-A | Polyethylene silicon compounds | RHONE-POULENC INDUSTRIES (FR) | 1980-06-17 | — | — | US | disclosed |
| US-4147711-A | Ethylenic silicon compounds and thermoplastic elastomers obtained therefrom | RHONE-POULENC INDUSTRIES (FR) | 1979-04-03 | — | — | US | disclosed |
| US-4145508-A | Polysiloxane thermoplastic elastomers | RHONE-POULENC INDUSTRIES (FR) | 1979-03-20 | — | — | US | disclosed |
| US-4088670-A | P-(DIMETHYLVINYLSILYL-METHOXY)-BENZOYL CHLORIDE FROM DIMETHYLVINYL-CHLOROMETHYLSILANE AND A P-HYDROXYBENZOIC ACID | RHONE-POULENC INDUSTRIES (FR) | 1978-05-09 | — | — | US | disclosed |