SCHEMBL6906782

SCHEMBL6906782

Cc1ccccc1-c1ccccc1C(=O)OOC(=O)c1ccccc1-c1ccccc1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.47
TSHR P16473 2/20 0.44
KMT2A Q03164 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
SLC6A3 Q01959 4/20 0.42
SLC6A4 P31645 3/20 0.42
MCL1 Q07820 1/20 0.41
TACR1 P25103 1/20 0.40
LMNA P02545 2/20 0.40
SLC6A2 P23975 1/20 0.40
F2 P00734 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
HPGD P15428 3/20 0.40
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PLA2G7 Q13093 2/20 0.38
MEN1 O00255 1/20 0.38
ESR1 P03372 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9549 0.86 SLC6A3 (0.57) MYCTSHRKMT2AL3MBTL1SLC6A3
SCHEMBL28249154 0.86 SLC6A3 (0.49) MYCTSHRKMT2AL3MBTL1SLC6A3
SCHEMBL7058899 0.85 MYC (0.44) MYCTSHRKMT2AL3MBTL1SLC6A3
SCHEMBL27522301 0.85 MYC (0.49) MYCTSHRKMT2AL3MBTL1SLC6A3
SCHEMBL9756368 0.85 MYC (0.44) MYCTSHRKMT2AL3MBTL1SLC6A3
SCHEMBL3950053 0.83 TSHR (0.69) TSHRKMT2AL3MBTL1LMNANPC1
Bicarbonate SCHEMBL27492792 0.83 SLC6A3 (0.54) MYCTSHRKMT2ASLC6A3SLC6A4
SCHEMBL127127 0.83 NPC1 (0.53) TSHRKMT2AL3MBTL1LMNAF2
SCHEMBL3639048 0.82 MYC (0.42) MYCTSHRKMT2AL3MBTL1SLC6A3
SCHEMBL2267132 0.81 SLC6A3 (0.51) MYCTSHRKMT2ASLC6A3SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470186-A1 POLYPROPYLENE RESIN COMPOSITION Basell Poliolefine Italia S.p.A. (IT) 2004-10-27 EP disclosed
WO-2003062316-A1 POLYPROPYLENE RESIN COMPOSITION BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2003-07-31 WO disclosed