SCHEMBL7058899

SCHEMBL7058899

Cc1ccccc1-c1ccccc1C(=O)O[SiH3]

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.44
TSHR P16473 1/20 0.41
KMT2A Q03164 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SLC6A3 Q01959 4/20 0.40
SLC6A4 P31645 3/20 0.40
MCL1 Q07820 1/20 0.39
TACR1 P25103 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SLC6A2 P23975 1/20 0.38
HPGD P15428 2/20 0.38
PLA2G7 Q13093 2/20 0.36
MEN1 O00255 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6906782 0.85 MYC (0.47) MYCTSHRKMT2AL3MBTL1SLC6A3
SCHEMBL7052788 0.84 NPC1 (0.50) TSHRKMT2AL3MBTL1NPC1RAB9A
SCHEMBL9549 0.83 SLC6A3 (0.57) MYCTSHRKMT2AL3MBTL1SLC6A3
SCHEMBL28249154 0.83 SLC6A3 (0.49) MYCTSHRKMT2AL3MBTL1SLC6A3
SCHEMBL27522301 0.81 MYC (0.49) MYCTSHRKMT2AL3MBTL1SLC6A3
SCHEMBL9756368 0.81 MYC (0.44) MYCTSHRKMT2AL3MBTL1SLC6A3
Bicarbonate SCHEMBL27492792 0.80 SLC6A3 (0.54) MYCTSHRKMT2ASLC6A3SLC6A4
SCHEMBL3950053 0.80 TSHR (0.69) TSHRKMT2AL3MBTL1NPC1RAB9A
SCHEMBL3639048 0.79 MYC (0.42) MYCTSHRKMT2AL3MBTL1SLC6A3
SCHEMBL2267132 0.78 SLC6A3 (0.51) MYCTSHRKMT2ASLC6A3SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1006118-B1 Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond DOW CORNING ASIA LTD (JP) 2003-05-07 EP disclosed
EP-1085022-A1 A method of manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via Si-C- bonds Dow Corning Asia, Ltd. (JP) 2001-03-21 EP disclosed
US-6175031-B1 PLATINUM-CATALYZED HYDROSILYLATION BETWEEN SIH-SUBSTITUTED SILICON COMPOUNDS AND UNSATURATED GROUP-FUNCTIONAL ORGANIC OR ORGANOSILICON COMPOUNDS IN PRESENCE OF A (ACYLOXY)-FUNCTIONAL HYDROGENSILANE COMPOUND OR ACID AND HYDRO(ALKOXY)SILANE DOW CORNING ASIA, LTD. (JP) 2001-01-16 US disclosed
US-6111126-A Method for synthesizing organosilicon compounds that contain a functional group bonded to silicon across the Si-C bond DOW CORNING ASIA, LTD. (JP) 2000-08-29 US disclosed
EP-1006118-A2 Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond Dow Corning Asia, Ltd. (JP) 2000-06-07 EP disclosed
US-6060620-A Method for manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via SI--C bonds DOW CORNING ASIA, LTD. (JP) 2000-05-09 US disclosed