Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 7/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.31 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028884 | 0.67 | GPR3 (0.37) | GPR3KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL22931682 | 0.65 | MEN1 (0.52) | CES1PTPN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6567354 | 0.65 | MEN1 (0.52) | CES1PTPN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL20385081 | 0.65 | MEN1 (0.52) | CES1PTPN1KMT2ALMNASMN1; SMN2 | |
| Benzene SCHEMBL14537401 | 0.65 | MEN1 (0.52) | CES1PTPN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL31886 | 0.65 | MEN1 (0.52) | CES1PTPN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL20733764 | 0.62 | GPR3 (0.38) | CES1PTPN1GPR3SLC22A2SLC22A3 | |
| SCHEMBL7155149 | 0.62 | NR3C2 (0.56) | CES1PTPN1KMT2ALMNAMAPT | |
| Water SCHEMBL10955435 | 0.62 | CHKA (0.50) | CES1PTPN1KMT2ALMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1764754 | 0.62 | CHKA (0.50) | CES1PTPN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923589-B1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-09-15 | — | — | EP | disclosed |
| US-6268444-B1 | TITANIUM, ZIRCONIUM OR HAFNIUM COMPOUNDS FOR POLYMERIZATION | DOW CHEMICAL COMPANY | 2001-07-31 | — | — | US | disclosed |
| EP-0923589-A1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006727-A1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |