SCHEMBL6907224

SCHEMBL6907224

CCC(C)C(=O)c1c(O)c(CC=C(C)C)c(O)c2c(-c3ccccc3)cc(=O)oc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 18/20 1.00
EPAS1 Q99814 18/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31237267 1.00 HIF1A (1.00) HIF1AEPAS1
SCHEMBL6914633 0.93 HIF1A (1.00) HIF1AEPAS1
Isomesuol SCHEMBL16367909 0.91 HIF1A (0.84) HIF1AEPAS1
Isomammeisin SCHEMBL6914103 0.86 HIF1A (1.00) HIF1AEPAS1
Mesuol SCHEMBL29258072 0.84 HIF1A (0.84) HIF1AEPAS1
SCHEMBL30377279 0.82 HIF1A (0.78) HIF1AEPAS1
Mammeisin SCHEMBL31237557 0.82 HIF1A (1.00) HIF1AEPAS1
Mammeisin SCHEMBL6913744 0.82 HIF1A (1.00) HIF1AEPAS1
SCHEMBL29934508 0.82 HIF1A (1.00) HIF1AEPAS1
SCHEMBL29517117 0.76 HIF1A (0.70) HIF1AEPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040014806-A1 Methods and compositions for lowering levels of blood lipids PHARMACIA CORPORATION 2004-01-22 US claimed
US-20040014806-A1 Methods and compositions for lowering levels of blood lipids PHARMACIA CORPORATION 2004-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014806-A1 Methods and compositions for lowering levels of blood lipids SLC10A2, SLC10A1, FABP2 HIF1A 4785/4885EPAS1 2927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.