Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27725861 | 0.83 | KDM4E (0.50) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL9829190 | 0.79 | PKM (0.62) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL29452841 | 0.79 | PKM (0.62) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL339943 | 0.79 | PKM (0.62) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL9831364 | 0.79 | PKM (0.62) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL1837396 | 0.77 | KDM4E (0.53) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL6903273 | 0.74 | KDM4E (0.51) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL15822961 | 0.73 | KDM4E (0.52) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL29005574 | 0.73 | KDM4E (0.63) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL27651327 | 0.72 | KDM4E (0.49) | KDM4EALOX12CYP3A4TDP1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743754-B2 | A SULFONYLUREA AND ONE OR MORE SURFACTANTS COMPRISING AS STRUCTURAL ELEMENT AT LEAST 10 ALKYLENE OXIDE UNITS. | AVENTIS CROPSCIENCE GMBH (DE) | 2004-06-01 | — | — | US | disclosed |