Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | METAP2 | P50579 | 1/20 | 0.53 |
| ▸ | METAP1 | P53582 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1838784 | 0.86 | KDM4E (0.54) | KDM4EHSP90AA1MAPTLMNABRD4 | |
| SCHEMBL15822961 | 0.84 | KDM4E (0.52) | KDM4EHSP90AA1MAPTLMNABRD4 | |
| SCHEMBL27725861 | 0.81 | KDM4E (0.50) | KDM4EHSP90AA1MAPTLMNABRD4 | |
| SCHEMBL1830309 | 0.81 | FABP4 (0.36) | KDM4EHSP90AA1MAPTLMNABRD4 | |
| SCHEMBL27588126 | 0.77 | KDM4E (0.49) | KDM4EHSP90AA1MAPTLMNABRD4 | |
| SCHEMBL28505844 | 0.77 | KDM4E (0.58) | KDM4EHSP90AA1MAPTLMNABRD4 | |
| SCHEMBL6907929 | 0.77 | KDM4E (0.46) | KDM4EHSP90AA1MAPTLMNABRD4 | |
| SCHEMBL12533363 | 0.76 | KDM4E (0.56) | KDM4EHSP90AA1MAPTLMNABRD4 | |
| SCHEMBL8686129 | 0.74 | PARP1 (0.49) | KDM4EHSP90AA1MAPTLMNAMETAP2 | |
| SCHEMBL28507152 | 0.74 | KDM4E (0.59) | KDM4EHSP90AA1MAPTLMNABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943218-B1 | ALKOXYALKYL SPIROCYCLIC TETRAMIC ACIDS AND TETRONIC ACIDS | BAYER IP GMBH (DE) | 2015-05-06 | — | — | EP | claimed |
| EP-1552746-B1 | Selective heteroaryloxy-acetamide-based herbicides | BAYER IP GMBH (DE) | 2015-02-11 | — | — | EP | claimed |
| EP-2243362-B1 | Selective heteroaryloxy-acetamide-based herbicides | BAYER CROPSCIENCE AG (DE) | 2014-12-24 | — | — | EP | claimed |
| EP-2243363-B1 | Selective heteroaryloxy-acetamide-based herbicides | BAYER CROPSCIENCE AG (DE) | 2014-11-26 | — | — | EP | claimed |
| EP-2243361-B1 | Selective heteroaryloxy-acetamide-based herbicides | BAYER CROPSCIENCE AG (DE) | 2014-11-26 | — | — | EP | claimed |
| EP-1966135-B1 | 3'-ALKOXY-SPIROCYCLOPENTYL-SUBSTITUTED TETRAMIC AND TETRONIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2013-10-09 | — | — | EP | claimed |
| CN-101808989-B | Halogen alkoxy spirocyclic tetramic and tetronic acid derivatives | BAYER CROPSCIENCE AG | 2013-01-30 | — | — | CN | claimed |
| EP-2121597-B1 | TRIFLUOROMETHOXYPHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES AS PESTICIDES AND/OR HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-09-21 | — | — | EP | claimed |
| EP-1761490-B1 | 3'-ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2011-09-07 | — | — | EP | claimed |
| EP-1606254-B1 | 2,4,6-PHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2011-05-11 | — | — | EP | claimed |
| CN-101808989-A | Halogen alkoxy spirocyclic tetramic and tetronic acid derivatives | BAYER CROPSCIENCE AG | 2010-08-18 | — | — | CN | claimed |
| CN-101547899-A | Biphenyl-substituted spirocyclic keto-enols | BAYER CROPSCIENCE AG (DE) | 2009-09-30 | — | — | CN | claimed |
| EP-1429613-B1 | SELECTIVE HERBICIDES BASED ON SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES AND SAFENERS | BAYER CROPSCIENCE AG (DE) | 2007-01-17 | — | — | EP | claimed |
| EP-1221848-B1 | SELECTIVE HERBICIDES ON THE BASIS A N-ARYL-TRIAZOLINEONE | BAYER CROPSCIENCE AG (DE) | 2006-01-25 | — | — | EP | claimed |
| EP-1303189-B1 | ARYL SULFONYL AMINO CARBONYL TRIAZOLE BASED SELECTIVE HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2005-08-24 | — | — | EP | claimed |
| EP-2908639-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | Bayer Cropscience AG (DE) | 2015-08-26 | — | — | EP | disclosed |
| WO-2014060502-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-04-24 | — | — | WO | disclosed |
| CN-101808989-A | Halogen alkoxy spirocyclic tetramic and tetronic acid derivatives | BAYER CROPSCIENCE AG | 2010-08-18 | — | — | CN | disclosed |
| CN-101547899-A | Biphenyl-substituted spirocyclic keto-enols | BAYER CROPSCIENCE AG (DE) | 2009-09-30 | — | — | CN | disclosed |
| US-5380852-A | Plant safening agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-01-10 | — | — | US | disclosed |