Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ALPG | P10696 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL199580 | 1.00 | TSHR (0.60) | TSHRLMNASMN1; SMN2ALDH1A1ALPG | |
| SCHEMBL16595422 | 0.88 | TSHR (0.48) | TSHRLMNASMN1; SMN2ALDH1A1ALPG | |
| SCHEMBL7262475 | 0.78 | ESR1 (0.62) | TSHRSMN1; SMN2ALDH1A1TDP1ESR1 | |
| SCHEMBL4319988 | 0.78 | ESR1 (0.62) | TSHRSMN1; SMN2ALDH1A1TDP1ESR1 | |
| SCHEMBL467691 | 0.78 | ESR1 (0.62) | TSHRSMN1; SMN2ALDH1A1TDP1ESR1 | |
| SCHEMBL9558453 | 0.76 | TSHR (0.48) | TSHRLMNASMN1; SMN2ALDH1A1ALPG | |
| SCHEMBL6689869 | 0.76 | TSHR (0.60) | TSHRESR1ESR2ALOX5KDM4E | |
| SCHEMBL132554 | 0.76 | AOC3 (0.38) | TSHRLMNASMN1; SMN2ALDH1A1ALPG | |
| SCHEMBL6688835 | 0.76 | TSHR (0.60) | TSHRLMNAALDH1A1HPGDTDP1 | |
| SCHEMBL4328254 | 0.76 | TSHR (0.60) | TSHRLMNAALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040171862-A1 | Method for producing optically active cyanohydrins and their corresponding acids | CLARIANT GMBH (DE) | 2004-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171862-A1 | Method for producing optically active cyanohydrins and their corresponding acids | MVD, HPD, VNN1 | TSHR 4387/4885LMNA 1769/4885SMN1; SMN2 2972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.