SCHEMBL6908032

SCHEMBL6908032

CCCCc1cc(-n2nc3ccc(Cl)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
ADORA3 P0DMS8 7/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
TLR8 Q9NR97 1/20 0.34
TLR7 Q9NYK1 1/20 0.34
GAA P10253 2/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 1/20 0.34
MAPK8 P45983 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4647349 0.96 PTGS2 (0.35) NPC1RAB9AADORA3KMT2AGAA
SCHEMBL10880369 0.96 PTGS2 (0.35) NPC1RAB9AADORA3KMT2AGAA
SCHEMBL14423818 0.93 NPC1 (0.37) NPC1RAB9AKMT2AGAAKDM4E
SCHEMBL11454857 0.92 NPC1 (0.38) NPC1RAB9AADORA3KMT2AMEN1
SCHEMBL4207567 0.91 NPC1 (0.36) NPC1RAB9AKMT2AMEN1TLR8
SCHEMBL6834699 0.90 CNR2 (0.32) NPC1RAB9A
Propionic Acid SCHEMBL6295773 0.90 OXER1 (0.36) KMT2AGAA
SCHEMBL77250 0.89 NPC1 (0.37) NPC1RAB9AKMT2AMEN1GAA
SCHEMBL30240899 0.89 NPC1 (0.37) NPC1RAB9AKMT2AMEN1GAA
SCHEMBL29807700 0.89 HSPA5 (0.43) NPC1RAB9AKMT2AMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100390122-C Composite stabilizer for improving stability of tetrabromoethane TIANJING CHANGLUHAIJING GROUP (CN) 2008-05-28 CN claimed
CN-1919811-A Composite stabilizer for improving stability of tetrabromoethane TIANJING CHANGLUHAIJING GROUP (CN) 2007-02-28 CN claimed
CN-100390122-C Composite stabilizer for improving stability of tetrabromoethane TIANJING CHANGLUHAIJING GROUP (CN) 2008-05-28 CN disclosed
CN-1919811-A Composite stabilizer for improving stability of tetrabromoethane TIANJING CHANGLUHAIJING GROUP (CN) 2007-02-28 CN disclosed
US-20040039115-A1 Polyethylene resin composition MITSUI CHEMICALS, INC. (JP) 2004-02-26 US disclosed
EP-1002833-B1 Polyolefin-based resin compositions and fabricated products produced therefrom MITSUI CHEMICALS INC (JP) 2003-09-03 EP disclosed
US-6534579-B1 Cyclic olefin resin and sorbitol derivative; heat resistance; transparent moldings MITSUI CHEMICALS, INC. (JP) 2003-03-18 US disclosed
EP-1081194-A1 THERMOPLASTIC RESIN COMPOSITION AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2001-03-07 EP disclosed
EP-1002833-A1 Polyolefin-based resin compositions and fabricated products produced therefrom Mitsui Chemicals, Inc. (JP) 2000-05-24 EP disclosed
EP-0517506-B1 Silver halide photographic product KONISHIROKU PHOTO IND (JP) 1999-03-17 EP disclosed
EP-0647880-B1 Method of processing silver halide photographic light-sensitive material KONISHIROKU PHOTO IND (JP) 1999-03-03 EP disclosed
EP-0146302-A1 Light-sensitive silver halide photographic material for direct-post and method for processing the same KONICA CORPORATION (JP) 1985-06-26 EP disclosed
US-4444875-A LAYER OF A TETRAZOLIUM COMPOUND KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-04-24 US disclosed
US-4427764-A DI-HIGHER ALKYL PHTHALATE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-01-24 US disclosed
US-4268620-A Method of processing of light-sensitive silver halide photographic material KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-05-19 US disclosed
US-4233400-A HIGH CONTRAST IMAGE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-11-11 US disclosed
US-4211835-A TETRAZOLIUM COMPOUND, BLACK AND WHITE, HIGH CONTRAST KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-07-08 US disclosed
US-4210715-A TETRAZOLIUM COMPOUND AND SENSITIZING DYE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-07-01 US disclosed
US-4175966-A NONDIFFUSING COMPOUND CAPABLE OF OXIDIZING HYDROQUINONE DEVELOPING AGENT KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1979-11-27 US disclosed
US-4169733-A PRETREATMENT WITH NITROGEN HETEROCYCLE SUBSTITUTED WITH MERCAPTO, THIOKETONE OR THIOETHER GROUP OF SILVER HALIDE EMULSION CONTAINING A TETRAZOLIUM COMPOUND KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1979-10-02 US disclosed