SCHEMBL6834699

SCHEMBL6834699

CCCCCCCCOCCCc1cc(-n2nc3ccc(Cl)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
P2RX7 Q99572 1/20 0.31
CNR1 P21554 4/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9340780 0.96 NPC1 (0.31) CNR2NPC1RAB9AP2RX7CNR1
SCHEMBL4647349 0.92 PTGS2 (0.35) CNR2NPC1RAB9ACNR1
SCHEMBL10880369 0.92 PTGS2 (0.35) CNR2NPC1RAB9ACNR1
SCHEMBL6908032 0.90 NPC1 (0.36) NPC1RAB9A
SCHEMBL7701744 0.89 CNR2 (0.38) CNR2NPC1RAB9ACNR1
SCHEMBL1922439 0.87 LMNA (0.38) NPC1RAB9A
Propionic Acid SCHEMBL6295773 0.87 OXER1 (0.36) CNR2CNR1
SCHEMBL78014 0.87 EPHX2 (0.41) CNR2CNR1
SCHEMBL13030430 0.87 EPHX2 (0.41) CNR2CNR1
SCHEMBL9229451 0.87 EPHX2 (0.41) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1401940-A1 POLYACETAL MOLDED ARTICLES STABILIZED AGAINST DISCOLORATION Ciba SC Holding AG (CH) 2004-03-31 EP disclosed
WO-2002088240-A1 POLYACETAL MOLDED ARTICLES STABILIZED AGAINST DISCOLORATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-11-07 WO disclosed
WO-2000018833-A1 SYNERGISTIC STABILIZING MIXTURES GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2000-04-06 WO disclosed