Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 4/20 | 0.33 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RPA1 | P27694 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4626589 | 1.00 | AKT2 (0.33) | AKT2AKT1AKT3BRD4TDO2 | |
| SCHEMBL2235659 | 0.84 | AKT2 (0.31) | AKT2AKT1AKT3BRD4TDO2 | |
| SCHEMBL4627172 | 0.82 | MEN1 (0.31) | KMT2AMAPT | |
| SCHEMBL2958316 | 0.82 | ALDH1A1 (0.31) | AKT2BRD4KMT2ACHEK1BRD2 | |
| SCHEMBL2236464 | 0.82 | ALDH1A1 (0.34) | AKT2AKT1AKT3 | |
| SCHEMBL4625148 | 0.77 | POLB (0.34) | MAPT | |
| SCHEMBL2239872 | 0.76 | PTGS1 (0.42) | KMT2AMAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL26133401 | 0.76 | — | — | |
| SCHEMBL2236714 | 0.74 | PTGS1 (0.40) | KMT2AMAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL26134370 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456217-A1 | METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM | Exxonmobil Chemical Patents Inc. (US) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003050131-A1 | METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2003-06-19 | — | — | WO | disclosed |