Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 4/20 | 0.32 |
| ▸ | RXRG | P48443 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2236889 | 0.85 | RXRB (0.33) | POLBHTR1DRXRBKDM4EGAA | |
| SCHEMBL4627172 | 0.81 | MEN1 (0.31) | MAPT | |
| SCHEMBL2236712 | 0.78 | — | — | |
| SCHEMBL27199679 | 0.77 | MEN1 (0.31) | — | |
| SCHEMBL6908173 | 0.77 | AKT2 (0.33) | MAPT | |
| SCHEMBL4626589 | 0.77 | AKT2 (0.33) | MAPT | |
| SCHEMBL6031753 | 0.77 | RXRB (0.36) | RXRBKDM4EGAAMAPTRXRA | |
| SCHEMBL29594786 | 0.77 | RXRB (0.36) | RXRBKDM4EGAAMAPTRXRA | |
| SCHEMBL2235094 | 0.76 | KIF11 (0.37) | RXRBRXRA | |
| SCHEMBL2233347 | 0.76 | POLB (0.34) | POLBHTR1DRXRBKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456217-B1 | METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM | EXXONMOBIL CHEM PATENTS INC (US) | 2008-02-13 | — | — | EP | disclosed |
| EP-1640377-B1 | Metallocenes and catalyst compositions derived therefrom | EXXONMOBIL CHEM PATENTS INC (US) | 2007-07-25 | — | — | EP | disclosed |
| US-7157591-B2 | Metallocenes and catalyst compositions derived therefrom | EXXONMOBIE CHEMICAL PATENTS INC. (US) | 2007-01-02 | — | — | US | disclosed |
| EP-1640377-A1 | Metallocenes and catalyst compositions derived therefrom | Exxonmobil Chemical Patents Inc. (US) | 2006-03-29 | — | — | EP | disclosed |
| US-20050037919-A1 | Metallocenes and catalyst compositions derived therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2005-02-17 | — | — | US | disclosed |
| EP-1456217-A1 | METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM | Exxonmobil Chemical Patents Inc. (US) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003050131-A1 | METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2003-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050037919-A1 | Metallocenes and catalyst compositions derived therefrom | HMOX1, RTF1, OPRM1 | POLB 908/4885HTR1D 1222/4885RXRB 3628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.