SCHEMBL6908211

SCHEMBL6908211

CO[Si](OC)(OC)C(=O)C1CCCN1N

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.35
KDM4E B2RXH2 1/20 0.33
KDM4C Q9H3R0 1/20 0.33
PEPD P12955 2/20 0.32
XPNPEP1 Q9NQW7 1/20 0.32
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31
CTSH P09668 1/20 0.31
CTSK P43235 1/20 0.31
LMNA P02545 1/20 0.31
CYP2C19 P33261 1/20 0.31
HSD17B10 Q99714 1/20 0.31
FKBP1A P62942 1/20 0.31
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6908217 1.00 MAPT (0.38) MAPTSMN1; SMN2ALDH1A1POLBKDM4E
SCHEMBL4737546 0.79 POLB (0.47) MAPTSMN1; SMN2ALDH1A1POLBPEPD
SCHEMBL8199687 0.79 POLB (0.47) MAPTSMN1; SMN2ALDH1A1POLBPEPD
SCHEMBL18884425 0.74 SMN1; SMN2 (0.49) MAPTSMN1; SMN2ALDH1A1POLBKDM4E
SCHEMBL16067903 0.74 SMN1; SMN2 (0.49) MAPTSMN1; SMN2ALDH1A1POLBKDM4E
SCHEMBL17560404 0.74 SMN1; SMN2 (0.40) MAPTSMN1; SMN2ALDH1A1POLBKDM4E
Hydrochloric Acid SCHEMBL17560460 0.72 SMN1; SMN2 (0.39) MAPTSMN1; SMN2ALDH1A1POLBKDM4E
SCHEMBL23999544 0.71 HSD17B10 (0.41) MAPTSMN1; SMN2ALDH1A1LMNACYP2C19
SCHEMBL7304578 0.71 FKBP1A (0.48) MAPTSMN1; SMN2ALDH1A1KDM4EFKBP1A
SCHEMBL3898404 0.71 HSD17B10 (0.41) MAPTSMN1; SMN2ALDH1A1LMNACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004067759-A2 REPLICATION OF NUCLEIC ACID ARRAYS CRANFIELD UNIVERSITY (GB) 2004-08-12 WO disclosed
EP-0798590-B1 Coating composition, transparent electrode substrate with such a coating, and liquid crystal display element with such a substrate TEIJIN LTD (JP) 2004-05-12 EP disclosed
US-6171663-B1 ELECTRODE SUBSTRATE COMPRISING A METAL OXIDE LAYER, A CURED POLYMER LAYER OBTAINED FROM CROSS-LINKING OF A SILICON MONOMER HAVING EPOXY AND ALKOXYSILYL GROUPS, SILICON MONOMER HAVING AMINO AND ALKOXYSILANE, A POLYMERIC VINYL ALCOHOLS TEIJIN LIMITED (JP) 2001-01-09 US disclosed
EP-0798590-A2 Liquid crystal display element with a transparent electrode substrate, and the transparent electrode substrate TEIJIN LIMITED (JP) 1997-10-01 EP disclosed