Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | PEPD | P12955 | 2/20 | 0.36 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17560460 | 0.98 | SMN1; SMN2 (0.39) | SMN1; SMN2MAPTALDH1A1POLBKDM4E | |
| SCHEMBL22978787 | 0.95 | ALDH1A1 (0.45) | SMN1; SMN2MAPTALDH1A1POLBKDM4E | |
| SCHEMBL4737546 | 0.85 | POLB (0.47) | SMN1; SMN2MAPTALDH1A1POLBPEPD | |
| SCHEMBL8199687 | 0.85 | POLB (0.47) | SMN1; SMN2MAPTALDH1A1POLBPEPD | |
| SCHEMBL18884425 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTALDH1A1POLBKDM4E | |
| SCHEMBL16067903 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTALDH1A1POLBKDM4E | |
| SCHEMBL3898404 | 0.74 | HSD17B10 (0.41) | SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7304578 | 0.74 | FKBP1A (0.48) | SMN1; SMN2MAPTALDH1A1KDM4EFKBP1A | |
| SCHEMBL6908217 | 0.74 | MAPT (0.38) | SMN1; SMN2MAPTALDH1A1POLBKDM4E | |
| SCHEMBL23999544 | 0.74 | HSD17B10 (0.41) | SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016034134-A1 | HETEROAROMATIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-03-10 | — | — | WO | disclosed |