Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335792 | 0.88 | AOC3 (0.42) | TAAR1AOC3HTR2AHRH1ESR1 | |
| SCHEMBL6905050 | 0.87 | TAAR1 (0.47) | TAAR1AOC3PKMHKDC1SLC6A2 | |
| SCHEMBL335664 | 0.84 | TAAR1 (0.59) | TAAR1AOC3PKMHTR2AHRH1 | |
| SCHEMBL7511093 | 0.77 | TAAR1 (0.59) | TAAR1AOC3PKMHTR2AHRH1 | |
| SCHEMBL7511084 | 0.77 | TAAR1 (0.59) | TAAR1AOC3PKMHTR2AHRH1 | |
| SCHEMBL6905217 | 0.76 | HPGD (0.33) | TAAR1AOC3HTR2AHRH1SLC6A4 | |
| SCHEMBL1263573 | 0.74 | AOC3 (0.48) | TAAR1AOC3HTR2AHRH1ESR1 | |
| SCHEMBL336023 | 0.73 | LMNA (0.46) | TAAR1AOC3HTR2AHRH1HKDC1 | |
| SCHEMBL9276354 | 0.72 | AOC3 (0.47) | TAAR1AOC3HTR2AHRH1ESR1 | |
| SCHEMBL233438 | 0.70 | LMNA (0.48) | TAAR1AOC3HTR2AHRH1HKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6703458-B2 | COORDINATION CATALYSTS; SPHERICAL MORPHOLOGY | BASELL POLYOLEFINE GMBH (DE) | 2004-03-09 | — | — | US | disclosed |
| US-20030018146-A1 | Catalyst components for the polymerization of olefins | EQUISTAR CHEMICALS, LP | 2003-01-23 | — | — | US | disclosed |