Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CCNH | P51946 | 1/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.43 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.41 |
| ▸ | S100A9 | P06702 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SGK1 | O00141 | 4/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3615693 | 0.74 | KMT2A (0.49) | TDP1CDK1CCNB1CCNA2CCND1 | |
| SCHEMBL3620528 | 0.74 | KMT2A (0.49) | TDP1CDK1CCNB1CCNA2CCND1 | |
| SCHEMBL3622320 | 0.72 | KMT2A (0.70) | CYP2C9MEN1POLBKMT2A | |
| SCHEMBL6753769 | 0.66 | CDK1 (0.54) | TDP1CDK1CCNB1CCNA2CCND1 | |
| SCHEMBL7563876 | 0.65 | CDK1 (0.45) | TDP1CDK1CCNB1CCNA2CCND1 | |
| SCHEMBL3259225 | 0.65 | TDP1 (0.45) | TDP1CDK1CCNB1CCNA2CCND1 | |
| SCHEMBL4962530 | 0.64 | HSD11B1 (0.58) | MEN1POLBKMT2A | |
| SCHEMBL16296008 | 0.64 | TDP1 (0.53) | TDP1CDK1CCNB1CCNA2CCND1 | |
| SCHEMBL7563873 | 0.64 | CDK1 (0.46) | TDP1CDK1CCNB1CCNA2CCND1 | |
| SCHEMBL16296180 | 0.64 | TDP1 (0.55) | TDP1CDK1CCNB1CCNA2CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040224996-A1 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB (SE) | 2004-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224996-A1 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | HSD11B1, HSD17B1, HSD11B2 | TDP1 797/4885CDK1 796/4885CCNB1 947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.