SCHEMBL6908595

SCHEMBL6908595

Cc1cc(CSc2cc(C(C)(C)C)cc(C(C)(C)C)c2O)c(O)c(C(C)(C)C)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.55
CYP2C19 P33261 6/20 0.54
CYP2C9 P11712 5/20 0.54
SMN1; SMN2 Q16637 5/20 0.54
HIF1A Q16665 4/20 0.54
CYP2D6 P10635 2/20 0.49
HSD17B10 Q99714 1/20 0.49
ALDH1A1 P00352 4/20 0.47
CA2 P00918 2/20 0.47
POLB P06746 1/20 0.47
TYR P14679 1/20 0.47
GAA P10253 2/20 0.37
MAPK1 P28482 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
XBP1 P17861 1/20 0.37
HTT P42858 1/20 0.37
CYP1A2 P05177 3/20 0.36
TSHR P16473 3/20 0.36
CYP3A4 P08684 2/20 0.36
HSP90AA1 P07900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10089368 0.79 CYP2C19 (0.47) HSPA5CYP2C19CYP2C9SMN1; SMN2HIF1A
SCHEMBL31281158 0.79 HSPA5 (0.83) HSPA5CYP2C19CYP2C9SMN1; SMN2HIF1A
Butylated Hydroxytoluene SCHEMBL28956621 0.79 ALDH1A1 (0.62) HSPA5CYP2C19CYP2C9SMN1; SMN2HIF1A
SCHEMBL14773884 0.78 CYP2C19 (0.43) HSPA5CYP2C19CYP2C9SMN1; SMN2HIF1A
SCHEMBL9180157 0.78 HSPA5 (0.70) HSPA5CYP2C19CYP2C9SMN1; SMN2HIF1A
SCHEMBL14471348 0.77 CYP2C19 (0.42) HSPA5CYP2C19CYP2C9SMN1; SMN2HIF1A
SCHEMBL8644657 0.77 HSPA5 (0.68) HSPA5CYP2C19CYP2C9SMN1; SMN2HIF1A
SCHEMBL29558774 0.76 HSPA5 (0.78) HSPA5CYP2C19CYP2C9SMN1; SMN2HIF1A
SCHEMBL2230912 0.76 HSPA5 (0.78) HSPA5CYP2C19CYP2C9SMN1; SMN2HIF1A
Butylated Hydroxytoluene SCHEMBL8034258 0.76 CA2 (0.82) HSPA5CYP2C19CYP2C9SMN1; SMN2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004078765-A2 CATALYSTS FOR THE POLYMERIZATION OF STYRENE BASF AKTIENGESELLSCHAFT (DE) 2004-09-16 WO disclosed