Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 19/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26224 | 1.00 | KIF11 (0.55) | KIF11 | |
| SCHEMBL18599373 | 0.98 | KIF11 (0.57) | KIF11 | |
| SCHEMBL10418791 | 0.87 | KIF11 (0.47) | KIF11 | |
| Trifluoroacetamide SCHEMBL28040960 | 0.85 | KIF11 (0.48) | KIF11 | |
| SCHEMBL11708407 | 0.85 | KIF11 (0.38) | KIF11 | |
| SCHEMBL9106215 | 0.84 | KIF11 (0.63) | KIF11 | |
| SCHEMBL19154882 | 0.83 | SIRT2 (0.50) | KIF11 | |
| SCHEMBL11295432 | 0.83 | KIF11 (0.37) | KIF11 | |
| SCHEMBL11705896 | 0.83 | KIF11 (0.37) | KIF11 | |
| SCHEMBL11615917 | 0.83 | KIF11 (0.37) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014160638-A1 | PROCESS OF MAKING PROSTACYCLIN COMPOUNDS WITH LINKER THIOL AND PEGYLATED FORMS | UNITED THERAPEUTICS CORPORATION (US) | 2014-10-02 | — | — | WO | disclosed |
| WO-2011012722-A1 | PRODRUGS CONTAINING AN AROMATIC AMINE CONNECTED BY AN AMIDO BOND TO A LINKER | ASCENDIS PHARMA AS (DK) | 2011-02-03 | — | — | WO | disclosed |