Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 16/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26224 | 0.85 | KIF11 (0.55) | KIF11 | |
| SCHEMBL6909006 | 0.85 | KIF11 (0.55) | KIF11 | |
| SCHEMBL18599373 | 0.83 | KIF11 (0.57) | KIF11 | |
| SCHEMBL10418791 | 0.77 | KIF11 (0.47) | KIF11 | |
| SCHEMBL16117463 | 0.75 | MEN1 (0.53) | KIF11 | |
| SCHEMBL23405872 | 0.74 | KIF11 (0.50) | KIF11 | |
| SCHEMBL34262 | 0.74 | KIF11 (0.50) | KIF11 | |
| SCHEMBL18670133 | 0.74 | KIF11 (0.50) | KIF11 | |
| SCHEMBL2634426 | 0.74 | KIF11 (0.50) | KIF11 | |
| SCHEMBL3792783 | 0.74 | KIF11 (0.50) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105228451-B | Process for preparing prostacyclin compounds having a thiol linker and a pegylated form | 联合治疗公司 | 2018-03-30 | — | — | CN | disclosed |
| CN-105228451-A | Process for preparing prostacyclin compounds having a thiol linker and a pegylated form | UNITED THERAPEUTICS CORP | 2016-01-06 | — | — | CN | disclosed |