Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171086 | 0.93 | MAPT (0.58) | MAPTALDH1A1CA2CA5ACYP2A6 | |
| SCHEMBL21027662 | 0.86 | MAPT (0.52) | MAPTALDH1A1CA2CA5ACYP2A6 | |
| SCHEMBL20861898 | 0.86 | MAPT (0.52) | MAPTALDH1A1CA2CA5ACYP2A6 | |
| SCHEMBL24296678 | 0.83 | ALDH1A1 (0.48) | MAPTALDH1A1CA2CA5ACYP2A6 | |
| P-Xylene SCHEMBL10339754 | 0.80 | ALDH1A1 (0.58) | MAPTALDH1A1CA2CYP2A6TDP1 | |
| SCHEMBL4408306 | 0.80 | ALDH1A1 (0.64) | MAPTALDH1A1CA2CA5APOLB | |
| P-Xylene SCHEMBL10339755 | 0.80 | ALDH1A1 (0.58) | MAPTALDH1A1CA2CYP2A6TDP1 | |
| SCHEMBL21632569 | 0.77 | MAPT (0.43) | MAPTALDH1A1CA2CA5ACYP2A6 | |
| SCHEMBL19605694 | 0.73 | MAPT (0.58) | MAPTALDH1A1CA2CA5APOLB | |
| SCHEMBL25056632 | 0.73 | ALDH1A1 (0.40) | MAPTALDH1A1CA2CA5APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187857-B1 | PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS | EASTMAN CHEM CO (US) | 2004-01-21 | — | — | EP | disclosed |