P-Xylene

P-Xylene

SCHEMBL10339754

Cc1ccc(C)cc1.N#CS.N#CS

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
CYP2A6 P11509 1/20 0.58
ACHE P22303 6/20 0.57
TDP1 Q9NUW8 3/20 0.57
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
IDO1 P14902 1/20 0.43
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
TSHR P16473 3/20 0.39
ALOX12 P18054 2/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 2/20 0.38
NPC1 O15118 1/20 0.38
NFKB1 P19838 1/20 0.38
S100A4 P26447 1/20 0.38
MTOR P42345 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Xylene SCHEMBL10339755 1.00 ALDH1A1 (0.58) ALDH1A1CYP2A6ACHETDP1CA1
Thiocyanic Acid SCHEMBL32679420 0.86 ALDH1A1 (0.68) ALDH1A1CYP2A6ACHETDP1IDO1
Toluene SCHEMBL28183150 0.84 TSHR (0.65) ALDH1A1CYP2A6ACHETDP1CA1
Toluene SCHEMBL7459103 0.84 TSHR (0.65) ALDH1A1CYP2A6ACHETDP1CA1
Toluene SCHEMBL5354973 0.82 TSHR (0.61) ALDH1A1CYP2A6ACHETDP1CA1
Thiocyanic Acid SCHEMBL32679422 0.82 RAB9A (0.52) ALDH1A1CYP2A6ACHETDP1TSHR
P-Xylene SCHEMBL1443687 0.81 ACHE (0.61) ALDH1A1CYP2A6ACHETDP1CA1
P-Xylene SCHEMBL461064 0.80 ACHE (0.89) ALDH1A1CYP2A6ACHETDP1CA1
P-Xylene SCHEMBL18229935 0.80
P-Xylene SCHEMBL28067071 0.80 ACHE (0.89) ALDH1A1CYP2A6ACHETDP1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2258987-A None JP disclosed
JP-H02258987-A METHOD FOR PREVENTING CORROSION OF STEEL PIPE FOR GEOTHERMAL WELL SANSHIN CHEM IND CO LTD 1990-10-19 JP disclosed