Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15780081 | 0.87 | AKT1 (0.50) | CXCR2AKT1LMNANPC1PKM | |
| SCHEMBL10908806 | 0.82 | ALDH1A1 (0.50) | LMNAHTTKDM4EKMT2AALDH1A1 | |
| SCHEMBL13197063 | 0.82 | CXCR2 (0.46) | CXCR2AKT1LMNANPC1PKM | |
| SCHEMBL6902374 | 0.81 | ELANE (0.47) | CXCR2AKT1KDM4EPOLBPPARD | |
| SCHEMBL24436869 | 0.81 | AURKA (0.42) | CXCR2LMNANPC1PKMHTT | |
| SCHEMBL1901977 | 0.78 | ALDH1A1 (0.45) | AKT1RAB9AKDM4EGAAKMT2A | |
| SCHEMBL4842042 | 0.77 | CYP3A4 (0.47) | AKT1RAB9AKDM4EGAAALDH1A1 | |
| SCHEMBL28471951 | 0.77 | TNFSF11 (0.47) | RAB9AKDM4EGAAALDH1A1CYP2C19 | |
| SCHEMBL4841858 | 0.76 | ALDH1A1 (0.54) | HTTKDM4EKMT2AALDH1A1HPGD | |
| SCHEMBL11324429 | 0.75 | ALDH1A1 (0.39) | AKT1RAB9AKDM4EGAAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040171864-A1 | Fluorinated aromatics | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-02 | — | — | US | claimed |
| US-20040171864-A1 | Fluorinated aromatics | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171864-A1 | Fluorinated aromatics | AFF1, AFF2, AFF4 | CXCR2 4840/4885AKT1 3874/4885LMNA 1172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.