Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.72 |
| ▸ | HBB | P68871 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | TK1 | P04183 | 2/20 | 0.49 |
| ▸ | PYGM | P11217 | 3/20 | 0.47 |
| ▸ | TYMP | P19971 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10323532 | 1.00 | LMNA (0.72) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL14193124 | 1.00 | LMNA (0.72) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL14564902 | 1.00 | LMNA (0.72) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL16774561 | 1.00 | LMNA (0.72) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL16774560 | 1.00 | LMNA (0.72) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL18266831 | 0.90 | LMNA (0.59) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL8928217 | 0.84 | TSHR (0.71) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL16774442 | 0.84 | TSHR (0.71) | LMNATSHRMAPTPMP22HBB | |
| Doxifluridine SCHEMBL15060572 | 0.84 | LMNA (1.00) | LMNATSHRMAPTPMP22HBB | |
| Doxifluridine SCHEMBL8095 | 0.84 | LMNA (1.00) | LMNATSHRMAPTPMP22HBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4166563-A1 | BRIDGED NUCLEOSIDE AND NUCLEOTIDE | LIID Pharmaceuticals, Inc. (JP) | 2023-04-19 | — | — | EP | disclosed |
| EP-1084266-B1 | THE APPLICATION OF 5'-MODIFIED NUCLEOTIDES IN MOLECULAR BIOLOGY AND MEDICINE | EUROP LAB MOLEKULARBIOLOG (DE) | 2004-06-30 | — | — | EP | disclosed |
| EP-1084266-A2 | 5'-MODIFIED NUCLEOTIDES AND THE APPLICATION THEREOF IN MOLECULAR BIOLOGY AND MEDICINE | Europäisches Laboratorium für Molekularbiologie (DE) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999053087-A2 | 5'-MODIFIED NUCLEOTIDES AND THE APPLICATION THEREOF IN MOLECULAR BIOLOGY AND MEDICINE | Europäisches Laboratorium für Molekularbiologie (EMBL) (DE) | 1999-10-21 | — | — | WO | disclosed |