Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6652251 | 0.83 | TDP1 (0.34) | TDP1SMN1; SMN2SLC22A6 | |
| SCHEMBL6652257 | 0.83 | TDP1 (0.34) | TDP1SMN1; SMN2SLC22A6 | |
| SCHEMBL9567921 | 0.80 | TDP1 (0.39) | TDP1SMN1; SMN2FOLH1SLC22A6 | |
| SCHEMBL5383912 | 0.78 | ALDH1A1 (0.37) | TDP1SMN1; SMN2FOLH1SLC22A6 | |
| SCHEMBL5383907 | 0.78 | ALDH1A1 (0.37) | TDP1SMN1; SMN2FOLH1SLC22A6 | |
| SCHEMBL8525881 | 0.77 | POLB (0.37) | TDP1SMN1; SMN2FOLH1SLC22A6 | |
| SCHEMBL19170131 | 0.74 | SLC22A6 (0.33) | TDP1SMN1; SMN2SLC22A6 | |
| SCHEMBL10691405 | 0.74 | TDP1 (0.33) | TDP1SMN1; SMN2SLC22A6 | |
| SCHEMBL30293 | 0.71 | TDP1 (0.48) | TDP1SMN1; SMN2FOLH1SLC22A6 | |
| SCHEMBL5157972 | 0.71 | TDP1 (0.48) | TDP1SMN1; SMN2FOLH1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395918-B1 | Conversion of a hydroxy group in certain alcohols into a fluorosulfonate ester or a trifluoromethylsulfonate ester | LOEWENTHAL HANS JACOB EDGAR (IL) | 2002-05-28 | — | — | US | claimed |
| EP-1075463-B1 | CONVERSION OF A HYDROXY GROUP IN CERTAIN ALCOHOLS INTO A FLUOROSULFONATE ESTER OR A TRIFLUOROMETHYLSULFONATE ESTER | LOEWENTHAL HANS JACOB EDGAR (IL) | 2004-06-16 | — | — | EP | disclosed |
| EP-1075463-A1 | CONVERSION OF A HYDROXY GROUP IN CERTAIN ALCOHOLS INTO A FLUOROSULFONATE ESTER OR A TRIFLUOROMETHYLSULFONATE ESTER | Loewenthal, Hans Jacob Edgar (IL) | 2001-02-14 | — | — | EP | disclosed |
| WO-1999055666-A1 | CONVERSION OF A HYDROXY GROUP IN CERTAIN ALCOHOLS INTO A FLUOROSULFONATE ESTER OR A TRIFLUOROMETHYLSULFONATE ESTER | LOEWENTHAL HANS JACOB EDGAR (IL) | 1999-11-04 | — | — | WO | disclosed |