Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6914527 | 0.82 | SKP2 (0.39) | SKP2NPC1HPGDMAPK1HTT | |
| SCHEMBL48321 | 0.81 | AOC3 (0.36) | HTTNOS2AOC3 | |
| SCHEMBL6910764 | 0.79 | AOC3 (0.39) | AOC3 | |
| SCHEMBL6909445 | 0.79 | TLR8 (0.33) | SKP2NOS2TLR8 | |
| SCHEMBL8540338 | 0.74 | AOC3 (0.38) | NPSR1AOC3 | |
| SCHEMBL9629542 | 0.74 | AOC3 (0.36) | AOC3 | |
| SCHEMBL6910768 | 0.74 | AOC3 (0.32) | AOC3 | |
| SCHEMBL9803730 | 0.73 | AOC3 (0.35) | HTTNOS2AOC3KDM4E | |
| SCHEMBL10430962 | 0.73 | SKP2 (0.48) | SKP2NPC1HPGDMAPK1HTT | |
| SCHEMBL9179742 | 0.72 | ALDH1A1 (0.36) | HTTAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265940-B1 | AROMATIC AMINE CURATIVES AND THEIR USE | ALBERMARLE CORP (US) | 2004-10-27 | — | — | EP | disclosed |
| US-6509434-B1 | Condensation polymerization of alkylthiated mononuclear aromatic amines and isocyanate prepolymer to produce polyurethanes, polyureaurethanes and/or polyureas | ALBEMARLE CORPORATION | 2003-01-21 | — | — | US | disclosed |