SCHEMBL8540338

SCHEMBL8540338

CCSc1cc(SCC)c(N)c(SCC)c1N

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.38
ALDH1A1 P00352 2/20 0.32
MAPT P10636 1/20 0.32
PPARG P37231 1/20 0.32
BLM P54132 1/20 0.32
NCOA2 Q15596 1/20 0.32
NCOA1 Q15788 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31
HSP90AA1 P07900 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48603 0.89 ALDH1A1 (0.34) AOC3ALDH1A1MAPT
SCHEMBL5522764 0.84 ALDH1A1 (0.33) AOC3ALDH1A1MAPT
SCHEMBL14776649 0.83 AOC3 (0.32) AOC3
SCHEMBL48321 0.83 AOC3 (0.36) AOC3ALDH1A1MAPTHSP90AA1
SCHEMBL6909445 0.82 TLR8 (0.33)
SCHEMBL6910764 0.81 AOC3 (0.39) AOC3
SCHEMBL9131493 0.81 SLC6A4 (0.32) HTR2AHTR2CHTR2B
SCHEMBL8764612 0.80
SCHEMBL1797285 0.79
SCHEMBL9184128 0.78 ALDH1A1 (0.40) ALDH1A1MAPTHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0591059-B1 Use of sulfur-containing metaphenylenediamines for dyeing keratinic fibers and new sulfur-containing metaphenylenediamines OREAL (FR) 1998-04-15 EP disclosed
US-5393806-A Adding a curing accelerator composition containing a mixture of a boron halide and an imidazole ALBEMARLE CORPORATION (US) 1995-02-28 US disclosed
US-5166115-A Polyurethanes ALBERMARLE CORPORATION 1992-11-24 US disclosed
US-5143942-A Polyureurethanes from Alkylthio-Substituted Toluenediamines ETHYL CORPORATION (US) 1992-09-01 US disclosed