SCHEMBL6909604

SCHEMBL6909604

C[Si](C)(C1=C(CC2=Cc3cccc4cccc2c34)[CH]c2ccccc21)C1=C(CC2=Cc3cccc4cccc2c34)[CH]c2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
S100A4 P26447 1/20 0.32
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
ATM Q13315 1/20 0.30
HSD17B10 Q99714 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6240155 0.71 SETD7 (0.30)
SCHEMBL7639637 0.71 MAPK1 (0.40) MAPK1MEN1MAPTKMT2AS100A4
SCHEMBL4512216 0.69 MEN1 (0.47) MAPK1MEN1MAPTKMT2AS100A4
SCHEMBL7195529 0.66 MAPK1 (0.44) MAPK1MEN1MAPTKMT2AS100A4
SCHEMBL131339 0.66 MAPK1 (0.47) MAPK1MEN1MAPTKMT2AS100A4
SCHEMBL130314 0.66 MAPK1 (0.47) MAPK1MEN1MAPTKMT2AS100A4
SCHEMBL130313 0.66 MAPK1 (0.47) MAPK1MEN1MAPTKMT2AS100A4
SCHEMBL131338 0.66 MAPK1 (0.47) MAPK1MEN1MAPTKMT2AS100A4
SCHEMBL129396 0.66 MEN1 (0.47) MAPK1MEN1MAPTKMT2AS100A4
SCHEMBL10424232 0.66 MAPK1 (0.47) MAPK1MEN1MAPTKMT2AS100A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6143686-A FOR ADDITION POLYMERIZATION OF ALPHA OLEFINS, SUCH AS PROPYLENE TO PRODUCE STEREOSPECIFIC POLMER EXXON CHEMICAL PATENTS, INC. (US) 2000-11-07 US claimed
EP-1373337-A2 PROPYLENE POLYMERS FOR FILMS Exxonmobil Chemical Patents Inc. (US) 2004-01-02 EP disclosed
WO-2002070572-A2 PROPYLENE POLYMERS FOR FILMS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-09-12 WO disclosed