Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4512216 | 0.75 | MEN1 (0.47) | MAPK1MEN1MAPTKMT2AS100A4 | |
| SCHEMBL2948401 | 0.72 | HSPA5 (0.31) | — | |
| SCHEMBL130313 | 0.72 | MAPK1 (0.47) | MAPK1MEN1MAPTKMT2AS100A4 | |
| SCHEMBL131338 | 0.72 | MAPK1 (0.47) | MAPK1MEN1MAPTKMT2AS100A4 | |
| SCHEMBL129395 | 0.72 | MAPK1 (0.52) | MAPK1MEN1MAPTKMT2AS100A4 | |
| SCHEMBL131339 | 0.72 | MAPK1 (0.47) | MAPK1MEN1MAPTKMT2AS100A4 | |
| SCHEMBL130314 | 0.72 | MAPK1 (0.47) | MAPK1MEN1MAPTKMT2AS100A4 | |
| SCHEMBL129396 | 0.72 | MEN1 (0.47) | MAPK1MEN1MAPTKMT2AS100A4 | |
| SCHEMBL6909604 | 0.71 | MAPK1 (0.35) | MAPK1MEN1MAPTKMT2AS100A4 | |
| SCHEMBL7946577 | 0.71 | MAPK1 (0.37) | MAPK1MEN1MAPTKMT2AS100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1134227-A2 | Methylene-bridged biscyclopentadienyl compounds | Basell Polyolefine GmbH (DE) | 2001-09-19 | — | — | EP | claimed |
| US-6255508-B1 | COORDINATION CATALYST; ALPHA-OLEFIN POLYMERIZATION CATALYST | TARGOR GMBH (DE) | 2001-07-03 | — | — | US | claimed |
| US-5945553-A | Process for preparing a methylene-bridged biscyclopentadienyl compound | TARGOR GMBH (DE) | 1999-08-31 | — | — | US | claimed |
| US-6369253-B1 | FORMATION OF AMINE AND OXYGEN SILANE BONDS TO FORM METALLOCENES | SRI INTERNATIONAL | 2002-04-09 | — | — | US | disclosed |
| EP-0832866-B1 | Process for the preparation of methylene-bridged biscyclopentadienyl compounds | BASELL POLYOLEFINE GMBH (DE) | 2002-01-09 | — | — | EP | disclosed |
| EP-1134227-A2 | Methylene-bridged biscyclopentadienyl compounds | Basell Polyolefine GmbH (DE) | 2001-09-19 | — | — | EP | disclosed |
| US-6255508-B1 | COORDINATION CATALYST; ALPHA-OLEFIN POLYMERIZATION CATALYST | TARGOR GMBH (DE) | 2001-07-03 | — | — | US | disclosed |
| WO-2000058323-A1 | METALLOCENE COMPOUNDS WITH SILOXAZOL LIGANDS | SRI INTERNATIONAL (US) | 2000-10-05 | — | — | WO | disclosed |
| US-6048992-A | Metallocene compounds from amino alcohol-derived ligands | SRI INTERNATIONAL (US) | 2000-04-11 | — | — | US | disclosed |
| US-5945553-A | Process for preparing a methylene-bridged biscyclopentadienyl compound | TARGOR GMBH (DE) | 1999-08-31 | — | — | US | disclosed |
| EP-0832866-A2 | Process for the preparation of methylene-bridged biscyclopentadienyl compounds | TARGOR GmbH (DE) | 1998-04-01 | — | — | EP | disclosed |