Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1454886 | 0.79 | NPSR1 (0.46) | L3MBTL1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9887 | 0.76 | KMT2A (0.56) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL20414287 | 0.74 | FAAH (0.44) | FAAHPHGDHMGLLCA12CA1 | |
| Alcohol SCHEMBL11357181 | 0.73 | CHKA (0.48) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL25007825 | 0.72 | FAAH (0.39) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL25645809 | 0.72 | FAAH (0.43) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL22276261 | 0.72 | FAAH (0.42) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL17951768 | 0.72 | FAAH (0.56) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL14217912 | 0.71 | FAAH (0.50) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL25137431 | 0.71 | FAAH (0.50) | FAAHPHGDHMGLLCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815183-B1 | Plasmodium sp. chitinase | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2004-11-09 | — | — | US | disclosed |