Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23438276 | 0.77 | FAAH (0.44) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL6909714 | 0.72 | FAAH (0.47) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL14217912 | 0.72 | FAAH (0.50) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL14608948 | 0.72 | FAAH (0.50) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL19959754 | 0.69 | ESR1 (0.44) | ALDH1A1 | |
| SCHEMBL194085 | 0.69 | HTT (0.46) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL28250176 | 0.69 | ALDH1A1 (0.45) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL21480196 | 0.69 | LMNA (0.43) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL9887 | 0.67 | KMT2A (0.56) | ALDH1A1NPC1RAB9ASMN1; SMN2POLQ | |
| SCHEMBL13448239 | 0.67 | HTT (0.44) | FAAHPHGDHMGLLCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129402-A1 | HYDROXYPYRROLIDINE DERIVATIVE AND MEDICINAL APPLICATION THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2023-02-08 | — | — | EP | disclosed |