Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.46 |
| ▸ | RAB9A | P51151 | 10/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.41 |
| ▸ | RELA | Q04206 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435900 | 0.74 | ALDH1A1 (0.48) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL11919638 | 0.73 | NPC1 (0.43) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL28983466 | 0.72 | NPC1 (0.47) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL30423061 | 0.71 | NPC1 (0.46) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL13569244 | 0.70 | MAPT (0.50) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL15726368 | 0.70 | ALDH1A1 (0.44) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL13218858 | 0.69 | MAPT (0.51) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL13084364 | 0.68 | ALDH1A1 (0.48) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL30384077 | 0.68 | NPC1 (0.43) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL13416589 | 0.68 | MAOA (0.63) | NPC1RAB9APOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767809-B1 | CURE-INDICATING MOLDING AND COATING COMPOSITION | MINNESOTA MINING & MFG (US) | 2004-01-21 | — | — | EP | disclosed |
| US-5596025-A | POLYSILOXANE CURABLE BY HYDROSILATION REACTION, COLOR CHANGE ON CURING | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-01-21 | — | — | US | disclosed |
| US-5583178-A | ADDITION POLYMER AND A CURE INDICATING DYE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-12-10 | — | — | US | disclosed |