SCHEMBL6910367

SCHEMBL6910367

CC(C)OC(=O)N(C(=O)[C@@H](N)C(C)C)[C@H](c1ccc(Cl)cc1)C(C)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
PRCP P42785 3/20 0.34
CXCR3 P49682 8/20 0.34
ADRB2 P07550 1/20 0.33
FFAR2 O15552 1/20 0.33
POLB P06746 2/20 0.32
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5970175 1.00 MEN1 (0.36) MEN1KMT2ACYP2D6CYP2C9CYP2C19
SCHEMBL6905748 1.00 MEN1 (0.36) MEN1KMT2ACYP2D6CYP2C9CYP2C19
SCHEMBL6912541 0.90 ALOX5 (0.35) CYP2C19
SCHEMBL6910851 0.87 AKR1C3 (0.38) CYP2D6CYP2C9CYP2C19
SCHEMBL6909942 0.85 DPP4 (0.34)
SCHEMBL6913172 0.80 KMT2A (0.44) MEN1KMT2ACYP2D6CYP2C9CYP2C19
SCHEMBL5023731 0.80 KMT2A (0.44) MEN1KMT2ACYP2D6CYP2C9CYP2C19
SCHEMBL5026042 0.80 KMT2A (0.44) MEN1KMT2ACYP2D6CYP2C9CYP2C19
SCHEMBL6910809 0.76 L3MBTL1 (0.36) MEN1KMT2ACYP2D6CYP2C9CYP2C19
SCHEMBL5970095 0.76 L3MBTL1 (0.36) MEN1KMT2ACYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1028125-B1 Dipeptide compounds having fungicidal activity and their agronomic use ISAGRO RICERCA SRL (IT) 2004-01-28 EP claimed