SCHEMBL69105

SCHEMBL69105

COc1cc(O)cc(Cl)c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 5/20 0.57
PTGS2 P35354 4/20 0.57
CYP3A4 P08684 2/20 0.54
MAPT P10636 2/20 0.54
HSD17B10 Q99714 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
MAOB P27338 1/20 0.45
ERN1 O75460 1/20 0.44
HPGD P15428 1/20 0.44
CRHBP P24387 1/20 0.44
CRHR2 Q13324 1/20 0.44
LMNA P02545 2/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA3 P07451 1/20 0.42
PKM P14618 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70379 0.83 ALOX5 (0.70) ALOX5PTGS2CYP3A4MAPTKMT2A
SCHEMBL10663410 0.82 CYP3A4 (0.56) ALOX5PTGS2CYP3A4MAPTHSD17B10
SCHEMBL9332746 0.82 ERN1 (0.58) ALOX5PTGS2CYP3A4MAPTHSD17B10
Ethane SCHEMBL27660205 0.80 ALOX5 (0.67) ALOX5PTGS2CYP3A4MAPTKMT2A
Methoxymethane SCHEMBL8720647 0.80 HSD17B10 (0.52) ALOX5PTGS2CYP3A4MAPTHSD17B10
SCHEMBL11857409 0.80 ERN1 (0.53) ALOX5PTGS2MAPTHSD17B10MEN1
SCHEMBL2388019 0.80 CYP3A4 (0.71) ALOX5PTGS2CYP3A4MAPTHSD17B10
SCHEMBL9396866 0.78 KMT2A (0.47) ALOX5PTGS2CYP3A4MAPTHSD17B10
SCHEMBL17974472 0.78 ERN1 (0.55) ALOX5PTGS2HSD17B10MEN1KMT2A
SCHEMBL1438002 0.78 THRB (0.60) ALOX5PTGS2CYP3A4MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 ALOX5 899/4885PTGS2 2866/4885CYP3A4 2028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.