Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGD | P52209 | 4/20 | 0.80 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
| ▸ | PGK1 | P00558 | 1/20 | 0.44 |
| ▸ | PGK2 | P07205 | 1/20 | 0.44 |
| ▸ | TPI1 | P60174 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15653993 | 0.95 | PGD (0.77) | PGDMPIPGK1PGK2TPI1 | |
| SCHEMBL15694600 | 0.95 | PGD (0.77) | PGDMPIPGK1PGK2TPI1 | |
| SCHEMBL2219243 | 0.89 | PGD (1.00) | PGDMPIPGK1PGK2TPI1 | |
| SCHEMBL16798059 | 0.89 | PGD (1.00) | PGDMPIPGK1PGK2TPI1 | |
| SCHEMBL16798058 | 0.89 | PGD (1.00) | PGDMPIPGK1PGK2TPI1 | |
| SCHEMBL15694950 | 0.87 | PGD (0.71) | PGDMPIPGK1PGK2TPI1 | |
| SCHEMBL20475910 | 0.79 | PGD (0.78) | PGDMPIPGK1PGK2 | |
| SCHEMBL20475925 | 0.79 | PGD (0.78) | PGDMPIPGK1PGK2 | |
| SCHEMBL4330445 | 0.79 | PGD (0.78) | PGDMPIPGK1PGK2 | |
| SCHEMBL4330442 | 0.79 | PGD (0.78) | PGDMPIPGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743598-B2 | SIMULTANEOUSLY ASSESSING MICROBIAL PHOSPHOGLUCOSE ISOMERASE, KETOL-ISOMERASE AND GLUCOSAMINE-6-PHOSPHATE ACETYLTRANSFERASE ACTIVITIES | MYCOLOGICS, INC. | 2004-06-01 | — | — | US | disclosed |
| US-20030194758-A1 | Methods for the identification of fungal glucose utilization inhibitors and antifungal agents | MYCOLOGICS, INC. | 2003-10-16 | — | — | US | disclosed |