SCHEMBL2219243

SCHEMBL2219243

O=C(NO)[C@H](O)[C@H](O)COP(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PGD P52209 4/20 1.00
MPI P34949 1/20 0.48
PGK1 P00558 1/20 0.47
PGK2 P07205 1/20 0.47
TPI1 P60174 1/20 0.44
S1PR2 O95136 2/20 0.36
S1PR1 P21453 2/20 0.36
S1PR3 Q99500 2/20 0.36
S1PR5 Q9H228 1/20 0.36
PLA2G4A P47712 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16798059 1.00 PGD (1.00) PGDMPIPGK1PGK2TPI1
SCHEMBL16798058 1.00 PGD (1.00) PGDMPIPGK1PGK2TPI1
SCHEMBL6910642 0.89 PGD (0.80) PGDMPIPGK1PGK2TPI1
SCHEMBL15653993 0.87 PGD (0.77) PGDMPIPGK1PGK2TPI1
SCHEMBL15694600 0.87 PGD (0.77) PGDMPIPGK1PGK2TPI1
SCHEMBL15694950 0.83 PGD (0.71) PGDMPIPGK1PGK2TPI1
SCHEMBL4317467 0.81 PGD (0.69) PGDMPIPGK1PGK2TPI1
SCHEMBL420471 0.78 PGD (1.00) PGDMPIPGK1PGK2
SCHEMBL20475915 0.78 PGD (1.00) PGDMPIPGK1PGK2
SCHEMBL20475914 0.78 PGD (1.00) PGDMPIPGK1PGK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100028334-A1 COMPOSITIONS AND METHODS TO POTENTIATE COLISTIN ACTIVITY TRUSTEES OF BOSTON UNIVERSITY (US) 2010-02-04 US claimed
WO-2008076806-A9 COMPOSITIONS AND METHODS TO POTENTIATE COLISTIN ACTIVITY UNIV BOSTON (US) 2008-08-07 WO claimed
WO-2008076806-A2 COMPOSITIONS AND METHODS TO POTENTIATE COLISTIN ACTIVITY TRUSTEES OF BOSTON UNIVERSITY (US) 2008-06-26 WO claimed
WO-2026099341-A1 BIOCONTAINMENT OF UNWANTED ENGINEERED CELLS USING NON-NATURAL AMINO ACIDS SNIPR BIOME APS (DK) 2026-05-15 WO disclosed
EP-4735462-A1 COMPOUNDS AND USES THEREFOR GLYCOSYNNOVATIONS PTY LTD (AU) 2026-05-06 EP disclosed
US-12564596-B2 Agents and methods for modulating pathogen activity GRIFFITH UNIVERSITY (AU) 2026-03-03 US disclosed
EP-4659014-A1 EMULSION-BASED THICK-FILM ANTIFOULING COATING FOR HIGHLY SENSITIVE ELECTROCHEMICAL SENSING President And Fellows Of Harvard College (US) 2025-12-10 EP disclosed
US-20250195501-A1 CELL ENTRY-MODULATING AGENTS AND USES THEREFOR GRIFFITH UNIVERSITY (AU) 2025-06-19 US disclosed
WO-2025000059-A1 COMPOUNDS AND USES THEREFOR Glycosynnovations Pty Ltd (AU) 2025-01-02 WO disclosed
CN-118986994-A Agents and methods for modulating pathogen activity 格里菲斯大学 2024-11-22 CN disclosed
WO-2024197225-A1 REDOX ACTIVE ANTIFOULING COATINGS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-09-26 WO disclosed
EP-2238157-A2 ENGINEERED BACTERIOPHAGES AS ADJUVANTS FOR ANTIMICROBIAL AGENTS AND COMPOSITIONS AND METHODS OF USE THEREOF Trustees of Boston University (US) 2010-10-13 EP disclosed
US-20100028334-A1 COMPOSITIONS AND METHODS TO POTENTIATE COLISTIN ACTIVITY TRUSTEES OF BOSTON UNIVERSITY (US) 2010-02-04 US disclosed
WO-2009108406-A2 ENGINEERED BACTERIOPHAGES AS ADJUVANTS FOR ANTIMICROBIAL AGENTS AND COMPOSITIONS AND METHODS OF USE THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2009-09-03 WO disclosed
EP-2084519-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING Los Alamos National Security, LLC (US) 2009-08-05 EP disclosed
WO-2009026328-A2 METHODS OF DELIVERY OF AGENTS TO LEUKOCYTES AND ENDOTHELIAL CELLS IMMUNE DISEASE INSTITUTE, INC. (US) 2009-02-26 WO disclosed
WO-2008127291-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-23 WO disclosed
US-20080220441-A1 Advanced drug development and manufacturing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2008-09-11 US disclosed
WO-2008076806-A9 COMPOSITIONS AND METHODS TO POTENTIATE COLISTIN ACTIVITY UNIV BOSTON (US) 2008-08-07 WO disclosed
WO-2008076806-A2 COMPOSITIONS AND METHODS TO POTENTIATE COLISTIN ACTIVITY TRUSTEES OF BOSTON UNIVERSITY (US) 2008-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250195501-A1 CELL ENTRY-MODULATING AGENTS AND USES THEREFOR ACE2, ACE, TMPRSS2 PGD 4431/4885MPI 736/4885PGK1 3602/4885
US-12564596-B2 Agents and methods for modulating pathogen activity C3AR1, HTR3A, CHRM3 PGD 3333/4885MPI 2796/4885PGK1 4498/4885
US-20100028334-A1 COMPOSITIONS AND METHODS TO POTENTIATE COLISTIN ACTIVITY VIP, C1QBP, CALCA PGD 1243/4885MPI 2165/4885PGK1 1026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.