Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6910615 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL5702834 | 0.77 | POLB (0.31) | — | |
| Hydrochloric Acid SCHEMBL5702765 | 0.74 | POLB (0.33) | — | |
| Hydrochloric Acid SCHEMBL6402550 | 0.73 | TSHR (0.34) | — | |
| Hydrochloric Acid SCHEMBL6911887 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL5702766 | 0.72 | POLB (0.32) | — | |
| Hydrochloric Acid SCHEMBL6407273 | 0.71 | L3MBTL1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL6908240 | 0.71 | POLB (0.31) | — | |
| Hydrochloric Acid SCHEMBL6910290 | 0.71 | POLB (0.31) | — | |
| Hydrochloric Acid SCHEMBL5702691 | 0.71 | POLB (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991677-B1 | PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH ALPHA-OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2004-06-16 | — | — | EP | disclosed |
| US-20020156209-A1 | Polymerization in the presence of metallocene catalysts with bridged bis-indenyl compounds | BASELL TECHNOLOGY COMANY BV (NL) | 2002-10-24 | — | — | US | disclosed |
| EP-0991677-A1 | PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH ALPHA-OLEFINS | Montell Technology Company bv (NL) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999054369-A1 | PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH ALPHA-OLEFINS | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1999-10-28 | — | — | WO | disclosed |