Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29044695 | 0.84 | CA12 (0.48) | LMNACYP2C19CA1CA2APP | |
| Trientine SCHEMBL29044705 | 0.82 | CA12 (0.50) | LMNACYP2C19CA1CA2PAOX | |
| SCHEMBL1435272 | 0.79 | CA12 (0.31) | LMNACA12CA14TDP1 | |
| SCHEMBL8419391 | 0.79 | CA1 (0.39) | LMNACA1CA2PAOXCA12 | |
| SCHEMBL10433042 | 0.77 | PTGS1 (0.33) | LMNACA12CA14TDP1 | |
| SCHEMBL299242 | 0.77 | CA12 (0.40) | LMNACYP2C19CA1CA2PAOX | |
| SCHEMBL19347270 | 0.76 | EPHX1 (0.52) | CA1CA2CA12CA14 | |
| SCHEMBL10656203 | 0.76 | EPHX1 (0.36) | CA2CA12CA14TDP1 | |
| Methylethylamine SCHEMBL1048048 | 0.75 | CA2 (0.33) | CA1CA2CA12CA14TDP1 | |
| Monoethanolamine SCHEMBL540866 | 0.75 | TSHR (0.44) | LMNASLC6A6CYP2C19BLMCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139041-A | Cationic color-protecting composition and color-protecting hair conditioner containing same | 广东植链科技发展有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-116847871-A | Skin care compositions and methods of use | 现代牧场股份有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-116139041-A | Cationic color-protecting composition and color-protecting hair conditioner containing same | 广东植链科技发展有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-116139041-A | Cationic color-protecting composition and color-protecting hair conditioner containing same | 广东植链科技发展有限公司 | 2023-05-23 | — | — | CN | disclosed |
| EP-1399608-A1 | SPANDEX CONTAINING QUATERNARY AMINE ADDITIVES | E. I. du Pont de Nemours and Company (US) | 2004-03-24 | — | — | EP | disclosed |
| WO-2003002788-A1 | SPANDEX CONTAINING QUATERNARY AMINE ADDITIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-01-09 | — | — | WO | disclosed |