Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969598 | 0.88 | — | — | |
| SCHEMBL9017462 | 0.87 | APP (0.42) | TSHRALDH1A1LMNASLC6A6CYP2C19 | |
| SCHEMBL5906890 | 0.83 | APP (0.48) | TSHRALDH1A1LMNASLC6A6CYP2C19 | |
| Methanesulfonic Acid Methyl Ester SCHEMBL27421560 | 0.83 | TSHR (0.56) | TSHRALDH1A1LMNASLC6A6CYP2C19 | |
| Propylamine SCHEMBL7726532 | 0.83 | LMNA (0.39) | TSHRLMNASLC6A6CYP2C19BLM | |
| Sulfuric Acid Dimethyl Ester SCHEMBL6417334 | 0.83 | TSHR (0.44) | TSHRALDH1A1LMNASLC6A6CYP2C19 | |
| Ethylamine SCHEMBL3467386 | 0.82 | — | — | |
| Propylamine SCHEMBL28235023 | 0.81 | LMNA (0.38) | TSHRLMNASLC6A6CYP2C19BLM | |
| SCHEMBL299242 | 0.80 | CA12 (0.40) | TSHRALDH1A1LMNACYP2C19CA2 | |
| Ethylamine SCHEMBL27588741 | 0.80 | CA2 (0.40) | TSHRLMNASLC6A6CYP2C19BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1076 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630784-B2 | Formula design for a solid laundry fabric softener | ECOLAB USA INC. (US) | 2026-05-19 | — | — | US | claimed |
| US-12577510-B2 | Dryer sheet and process of making | THE PROCTER & GAMBLE COMPANY (US) | 2026-03-17 | — | — | US | claimed |
| WO-2025229061-A1 | COMPOSITION FOR ANTI-GRAFFITI COATING AND METHOD FOR PREPARING THE COMPOSITION | O2-TABS DESINFEKTION GMBH (DE) | 2025-11-06 | — | — | WO | claimed |
| US-20250290010-A1 | HIGHLY ACIDIC LAUNDRY SOUR SOFTENER WITH EXTRA STABILITY, LAUNDRY FIRE MITIGATION, AND OILY SOIL REMOVAL PROPERTIES | ECOLAB USA INC. | 2025-09-18 | — | — | US | claimed |
| US-12344818-B2 | Highly acidic laundry sour softener with extra stability, laundry fire mitigation, and oily soil removal properties | ECOLAB USA INC. (US) | 2025-07-01 | — | — | US | claimed |
| US-20250034489-A1 | DRYER SHEET AND PROCESS OF MAKING | THE PROCTER & GAMBLE COMPANY | 2025-01-30 | — | — | US | claimed |
| CN-117306248-A | Concentrated softener composition | 广州立白企业集团有限公司 | 2023-12-29 | — | — | CN | claimed |
| CN-117015593-A | Use of enzymes for improving fragrance deposition | 诺维信公司 | 2023-11-07 | — | — | CN | claimed |
| WO-2023168301-A2 | HOME CARE COMPOSITIONS COMPRISING MICROBIALLY PRODUCED OIL AND DERIVATIVES THEREOF | C16 Biosciences, Inc. (US) | 2023-09-07 | — | — | WO | claimed |
| EP-4237521-A1 | LAUNDRY SOUR SOFTENER WITH EXTRA STABILITY AND ADDITIONAL BENEFITS OF LAUNDRY FIRE MITIGATION AND SUNSCREEN REMOVAL | Ecolab USA Inc. (US) | 2023-09-06 | — | — | EP | claimed |
| WO-1999045089-A1 | CONCENTRATED, STABLE, TRANSLUCENT OR CLEAR, FABRIC SOFTENING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1999-09-10 | — | — | WO | claimed |
| US-5942486-A | Dryer-activated laundry additive compositions with color care agents | THE PROCTER & GAMBLE COMPANY (US) | 1999-08-24 | — | — | US | claimed |
| WO-1999027046-A1 | LOW SOLVENT RINSE-ADDED FABRIC SOFTENERS HAVING INCREASED SOFTNESS BENEFITS | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-03 | — | — | WO | claimed |
| US-5804547-A | SUBSTRATE IN FORM OF SHEET CARRYING COLOR CARE COMPOSITION AND FABRIC SOFTENER | THE PROCTER & GAMBLE COMPANY (US) | 1998-09-08 | — | — | US | claimed |
| EP-0712435-B1 | DRYER-ACTIVATED FABRIC CONDITIONING AND ANTISTATIC COMPOSITIONS CONTAINING BIODEGRADABLE COMPOUNDS HAVING UNSATURATION | PROCTER & GAMBLE (US) | 1997-11-12 | — | — | EP | claimed |
| US-5559088-A | DIESTERS OF NON-ALLYLIC ALCOHOLS SLOWLY HYDROLYZE TO RELEASE PERFUME GRADUALLY | THE PROCTOR & GAMBLE COMPANY (US) | 1996-09-24 | — | — | US | claimed |
| EP-0712435-A1 | DRYER-ACTIVATED FABRIC CONDITIONING AND ANTISTATIC COMPOSITIONS CONTAINING BIODEGRADABLE COMPOUNDS HAVING UNSATURATION | THE PROCTER & GAMBLE COMPANY (US) | 1996-05-22 | — | — | EP | claimed |
| US-5476599-A | Containing a quaternary ammonium compound and a tertiary amine salt of a carboxylic acid | THE PROCTER & GAMBLE COMPANY (US) | 1995-12-19 | — | — | US | claimed |
| WO-1995004802-A1 | DRYER-ACTIVATED FABRIC CONDITIONING AND ANTISTATIC COMPOSITIONS CONTAINING BIODEGRADABLE COMPOUNDS HAVING UNSATURATION | THE PROCTER & GAMBLE COMPANY (US) | 1995-02-16 | — | — | WO | claimed |
| EP-0636356-A1 | Hair conditioner compositions containing fatty acid ester derivatives of alkanolamines | STEPAN COMPANY (US) | 1995-02-01 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630784-B2 | Formula design for a solid laundry fabric softener | SLC43A1, CLK4, CLK1 | TSHR 884/4885ALDH1A1 3088/4885LMNA 657/4885 |
| US-12577510-B2 | Dryer sheet and process of making | SAMM50, MAT1A, NOS3 | TSHR 2448/4885ALDH1A1 2106/4885LMNA 696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.