SCHEMBL6911272

SCHEMBL6911272

Fc1cccc([B-](c2cccc(F)c2)(c2cccc(F)c2)c2cccc(F)c2)c1.c1ccc([PH+](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 5/20 0.38
ACHE P22303 1/20 0.34
TAAR1 Q96RJ0 2/20 0.33
ESR2 Q92731 1/20 0.33
IDO1 P14902 1/20 0.33
TDO2 P48775 1/20 0.33
ADORA2A P29274 1/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
HPGD P15428 1/20 0.32
KCNN4 O15554 1/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
GFER P55789 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
PKM P14618 1/20 0.31
MAPK1 P28482 1/20 0.31
THPO P40225 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6913920 0.84 CYP1A2 (0.32) NFE2L2IDO1TDO2CYP1A2
SCHEMBL985844 0.83 ACHE (0.46) NFE2L2ACHETAAR1ESR2IDO1
Silver SCHEMBL1452545 0.81 ACHE (0.44) NFE2L2ACHETAAR1ESR2IDO1
Silver SCHEMBL29830980 0.81 ACHE (0.44) NFE2L2ACHETAAR1ESR2IDO1
SCHEMBL912803 0.81 ACHE (0.44) NFE2L2ACHETAAR1ESR2IDO1
Lithium Ion SCHEMBL1451578 0.81 ACHE (0.44) NFE2L2ACHETAAR1ESR2IDO1
Lithium Ion SCHEMBL29567744 0.81 ACHE (0.44) NFE2L2ACHETAAR1ESR2IDO1
SCHEMBL1450851 0.81 ACHE (0.44) NFE2L2ACHETAAR1ESR2IDO1
Tetraphenylphosphonium SCHEMBL5336026 0.81 NFE2L2 (0.38) NFE2L2ACHETAAR1ESR2IDO1
SCHEMBL29512287 0.79 ACHE (0.42) NFE2L2ACHETAAR1ESR2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0969010-B1 Transition metal compound and catalyst containing the same for polymerization of olefins JAPAN POLYOLEFINS CO LTD (JP) 2004-09-22 EP disclosed
US-6352953-B1 TRANSITION METAL COMPLEX HAVING 5-MEMBERED RING FORMED BY TRANSITION METAL COMPOUND OF GROUP IVB, TWO CARBONS, METAL OF GROUP IIIA AND HYDROGEN JAPAN POLYOLEFINS CO., LTD. (JP) 2002-03-05 US disclosed
US-6150544-A Transition metal compound and catalyst containing the same for polymerization of olefins JAPAN POLYOLEFINS CO., LTD. (JP) 2000-11-21 US disclosed
EP-0969010-A2 Transition metal compound and catalyst containing the same for polymerization of olefins Japan Polyolefins Co., Ltd. (JP) 2000-01-05 EP disclosed
EP-0714920-B1 Catalyst for polymerization of olefins NIPPON OIL CO LTD (JP) 1997-11-05 EP disclosed
EP-0768320-A1 Catalyst component and catalyst NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed
EP-0714920-A1 Catalyst for polymerization of olefins NIPPON OIL CO. LTD. (JP) 1996-06-05 EP disclosed