SCHEMBL691131

SCHEMBL691131

CCOc1ccc(/C=C/C(=O)O)cc1

nearest known ligand 0.77

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.69
RAB9A P51151 3/20 0.69
KDM4E B2RXH2 2/20 0.69
ALDH1A1 P00352 2/20 0.69
MAPT P10636 2/20 0.69
HTT P42858 1/20 0.69
KMT2A Q03164 1/20 0.69
POLB P06746 1/20 0.68
SMN1; SMN2 Q16637 2/20 0.67
THRB P10828 1/20 0.66
ATM Q13315 1/20 0.66
MAOB P27338 8/20 0.65
MAOA P21397 1/20 0.65
ABCG2 Q9UNQ0 1/20 0.63
RELA Q04206 1/20 0.62
TP53 P04637 1/20 0.61
EGFR P00533 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL691132 1.00 NPC1 (0.69) NPC1RAB9AKDM4EALDH1A1MAPT
Hydrochloric Acid SCHEMBL8023969 0.98 NPC1 (0.68) NPC1RAB9AKDM4EALDH1A1MAPT
SCHEMBL27766810 0.88 NPC1 (0.60) NPC1RAB9AKDM4EALDH1A1MAPT
Diethanolamine SCHEMBL5054343 0.88 KDM4E (0.57) NPC1RAB9AKDM4EALDH1A1MAPT
Diethanolamine SCHEMBL5054345 0.88 KDM4E (0.57) NPC1RAB9AKDM4EALDH1A1MAPT
SCHEMBL9556747 0.87 NPC1 (0.56) NPC1RAB9AKDM4EALDH1A1MAPT
SCHEMBL7969488 0.87 KDM4E (0.73) NPC1RAB9AKDM4EALDH1A1MAPT
SCHEMBL7969484 0.87 KDM4E (0.73) NPC1RAB9AKDM4EALDH1A1MAPT
SCHEMBL417823 0.86 ABCG2 (0.65) NPC1RAB9AKDM4EALDH1A1MAPT
SCHEMBL154581 0.86 ABCG2 (0.65) KMT2APOLBTHRBATMABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2328938-B1 RADICALLY FUNCTIONALIZED OLEFIN-BASED POLYMER WITH REDUCED MOLECULAR WEIGHT CHANGE AND METHOD DOW GLOBAL TECHNOLOGIES LLC (US) 2015-04-01 EP claimed
US-5961875-A Antifreeze/coolant composition containing cinnamic acid CCI CO., LTD. (JP) 1999-10-05 US claimed
US-20260001999-A1 HYDROPHILIC OIL REPELLENT POLYMER SUMITOMO CHEMICAL CO (JP) 2026-01-01 US disclosed
EP-4578895-A1 POLYMER, RESIN COMPOSITION, MOLDED BODY, AND POLYMER PRODUCTION METHOD Sumitomo Chemical Company, Limited (JP) 2025-07-02 EP disclosed
EP-4578894-A1 HYDROPHILIC OIL REPELLENT POLYMER Sumitomo Chemical Company, Limited (JP) 2025-07-02 EP disclosed
CN-119604562-A Hydrophilic oil-repellent polymer 住友化学株式会社 2025-03-11 CN disclosed
US-11999695-B2 YAP1 inhibitors that target the interaction of YAP1 with OCT4 H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) 2024-06-04 US disclosed
CN-114746154-B Cosmetic composition, use thereof and method for improving organoleptic properties 巴斯夫欧洲公司 2024-06-04 CN disclosed
WO-2024043326-A1 HYDROPHILIC OIL REPELLENT POLYMER 住友化学株式会社 2024-02-29 WO disclosed
WO-2024043327-A1 POLYMER, RESIN COMPOSITION, MOLDED BODY, AND POLYMER PRODUCTION METHOD 住友化学株式会社 2024-02-29 WO disclosed
US-20230234924-A1 YAP1 INHIBITORS THAT TARGET THE INTERACTION OF YAP1 WITH OCT4 H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. 2023-07-27 US disclosed
EP-0590919-A1 Therapeutic agents for parkinson's disease KYOWA HAKKO KOGYO CO., LTD. (JP) 1994-04-06 EP disclosed
EP-0565377-A1 Therapeutic agents for use in the treatment of parkinson's disease KYOWA HAKKO KOGYO CO., LTD. (JP) 1993-10-13 EP disclosed
US-RE32944-E Aromatic carboxylic amide derivatives Kissei Yakuhin Kogyo Kabushiki (JP) 1989-06-06 US disclosed
US-4189484-A Antihypertensive quinazoline derivatives MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) 1980-02-19 US disclosed
US-4070484-A Antiallergic composition containing aromatic carboxylic amide derivatives and method of using the same KISSEI PHARMACEUTICAL CO., LTD. (JA) 1978-01-24 US disclosed
US-4026896-A ANTIALLERGENS KISSEI YAKUHIN KOGYO KABUSHIKI KAISHA (KISSEI PHARMACEUTICAL CO. LTD.) (JA) 1977-05-31 US disclosed
US-3995054-A MITICIDES ZOECON CORPORATION (US) 1976-11-30 US disclosed
US-3975429-A Cyclopropanemethyl esters of cinnamic acid and derivatives thereof ZOECON CORPORATION (US) 1976-08-17 US disclosed
US-3940422-A ANTIALLERGEN KISSEI YAKUHIN KOGYO KABUSHIKI KAISHA (JA) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11999695-B2 YAP1 inhibitors that target the interaction of YAP1 with OCT4 YAP1, YES1, MYC NPC1 4862/4885RAB9A 2213/4885KDM4E 586/4885
US-20260001999-A1 HYDROPHILIC OIL REPELLENT POLYMER CCR1, H1-3, CCR3 NPC1 265/4885RAB9A 3950/4885KDM4E 3780/4885
US-20230234924-A1 YAP1 INHIBITORS THAT TARGET THE INTERACTION OF YAP1 WITH OCT4 YAP1, YES1, MYC NPC1 4862/4885RAB9A 2213/4885KDM4E 586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.