Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.51 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969488 | 1.00 | KDM4E (0.73) | KDM4EALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL7966458 | 0.88 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL1481792 | 0.88 | POLB (0.59) | KDM4EALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL1481794 | 0.88 | POLB (0.59) | KDM4EALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL7966464 | 0.88 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL691131 | 0.87 | NPC1 (0.69) | KDM4EALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL691132 | 0.87 | NPC1 (0.69) | KDM4EALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL7956707 | 0.85 | POLB (0.56) | KDM4EALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL7956711 | 0.85 | POLB (0.56) | KDM4EALDH1A1SMN1; SMN2POLBKMT2A | |
| Hydrochloric Acid SCHEMBL8023969 | 0.85 | NPC1 (0.68) | KDM4EALDH1A1SMN1; SMN2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277502-B1 | ORGANOSILICON POLYMERS; LIQUID CRYSALS | ROLIC AG (CH) | 2001-08-21 | — | — | US | disclosed |
| US-3987116-A | ETHYNYLARYL COMPOUNDS AND DERIVATIVES THEREOF | WILLIAM H. RORER, INC. (US) | 1976-10-19 | — | — | US | disclosed |